Transcription Factor
| Accessions: | UP00258A (UniPROBE 20160601) |
| Names: | 4921501K24, 5'-TG-3'-interacting factor 2, 5730599O09Rik, C80753, C81206, Homeobox protein TGIF2, TALE family homeobox, TGF(beta)-induced transcription factor 2, TGFB-induced factor 2, Tgif2 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q8C0Y1 |
| Description: | TGFB-induced factor 2 |
| Length: | 96 |
| Pfam Domains: | 17-73 Homeobox domain 34-73 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 DSDLGEDEGLLSLTGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNLSV 60 61 LQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGG |
| Interface Residues: | 17, 18, 19, 20, 22, 61, 62, 64, 65, 68, 69, 70, 72, 73, 87, 88, 89, 92, 93 |
| 3D-footprint Homologues: | 6fqp_B, 1zq3_P, 1mnm_C, 1puf_B, 2ld5_A, 1au7_A, 1le8_A, 1k61_B, 6fqq_E, 2hdd_A, 4xrm_B, 1du0_A, 7psx_B, 1le8_B, 5zjt_E, 2d5v_B, 1fjl_B, 2h1k_B, 2hos_A, 2p5l_D |
| Binding Motifs: | UP00258A_1 aacyAGCTGTCAAwmc |
| Binding Sites: | AACTGTCA AATGACAG ACCTGTCA ACTGACAG AGCTGTCA ATCTGTCA ATGACAGC ATGACAGG ATTGACAG CCTGTCAA CCTGTCAG CGCTGTCA CTGACAGC CTGTCAAA CTGTCAGA GCCTGTCA GCTGTCAA GCTGTCAC GGCTGTCA TCTGTCAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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