Transcription Factor

						

			
Accessions: T015196_1.02 (CISBP 1.02)

			
Names: Mitf, T015196_1.02;
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:bHLH
Length: 419
Pfam Domains:   212-258 Helix-loop-helix DNA-binding domain
  290-415 Domain of unknown function (DUF3371)
Sequence: 
(in bold interface residues)		   1 MQSESGIVADFEVGEEFHEEPKTYYELKSQPLKSSSSAEHSGASKPPLSSSTMTSRILLR   60
  61 QQLMREQMQEQERREQQQKLQAAQFMQQRVAVSQTPAINVSVPTTLPSATQVPMEVLKMD  120
 121 DVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYSNQGLPPPGLTISNSCPAN  180
 181 LPNIKRELTESEARALAKERQKKDNHNLSKFVERRRRFNINDRIKELGTLIPKSNDPDMR  240
 241 WNKGTILKASVDYIRKLQREQQRAKDLENRQKKLEHANRHLLLRVQELEMQARAHGLSLI  300
 301 PSTGLCSPDLVNRIIKQEPVLENCSQELVQHQADLTCTTTLDLTDGTITFTNNLGTMPES  360
 361 SPAYSIPRKMGSNLEDILMDDALSPVGVTDPLLSSVSPGASKTSSRRSSMSAEETEHAC
Interface Residues: 94, 206, 207, 210, 212, 213, 216, 217, 241, 243
3D-footprint Homologues: 2ihn_A, 7d8t_A, 4zpk_A, 5v0l_A, 1am9_A, 7ssa_L, 6g1l_A, 7xi3_A, 5nj8_D, 7f2f_B, 4h10_A, 1an4_A, 8osl_O, 2ypa_A, 5gnj_I, 8osl_P, 4h10_B, 5nj8_C, 5v0l_B
Binding Motifs: M0208_1.02 rrTCACGtGg
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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