Transcription Factor
| Accessions: | UP00415A (UniPROBE 20160601) |
| Names: | 2310011G17Rik, A130026I01Rik, BB162516, Elk4, ETS domain-containing protein Elk-4, member of ETS oncogene family, SAP-1, Sap1, Serum response factor accessory protein 1, SRF accessory protein 1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q99K98 |
| Description: | ELK4, member of ETS oncogene family: ETS domain-containing protein Elk-4 |
| Length: | 103 |
| Pfam Domains: | 4-85 Ets-domain |
| Sequence: (in bold interface residues) | 1 DSAITLWQFLLQLLQEPQNEHMICWTSNNGEFKLLQAEEVARLWGIRKNKPNMNYDKLSR 60 61 ALRYYYVKNIIKKVNGQKFVYKFVSYPEILKMDPLTVARIEGD |
| Interface Residues: | 50, 51, 56, 57, 59, 60, 61, 62, 63, 64, 65, 66, 69, 78 |
| 3D-footprint Homologues: | 5hdn_C, 3zp5_A, 2stt_A, 7jsa_J, 4mhg_A, 8ee9_F, 1dux_F, 4uno_A, 3jtg_A, 4l18_B, 1yo5_C, 1awc_A, 4lg0_B, 4bqa_A, 1bc8_C, 2w42_A, 4iri_A |
| Binding Motifs: | UP00415A_1 vtgwryTTCCGGyarc |
| Binding Sites: | AACCGGAA ACATCCGG ACCGGAAA ACCGGAAC ACCGGAAG ACCGGATG ACTTCCGG ATCCGGAA ATCCGGAT CACCGGAA CCGGAAAC CCGGAAGC CCGGATGC CGGAAATA CTTCCGGA CTTCCGGC GCCGGAAA TACCGGAA TCCGGAAA TTCCGGAA |
| Publications: | Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed] |
| Related annotations: | PaperBLAST |
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