Transcription Factor

						

			
Accessions: T131276_1.02 (CISBP 1.02)

			
Names: nhr-42, T131276_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 356
Pfam Domains:      8-76 Zinc finger, C4 type (two domains)
  134-338 Ligand-binding domain of nuclear hormone receptor
Sequence: 
(in bold interface residues)		   1 MTRQTTSQTCLICGDSADSLHFGALSCRACAAFFRRKVAGRRNIFRRCDRQCKVDTGMRK   60
  61 LCASCRYDKCLKVGMRESAVLSRLAKKNQNYKKSIVGSPDAYEPSTSTSDSVLENLQSAY  120
 121 HKLEETRKRVFNISETHVSQCCNYKRMNDVFFEDIKLVMEHLLETFKKSDISQEQEKLLC  180
 181 VHFMVPFILFEGGYKSTNSDLFYLPSGDFIDENRIEEYYSNPDDQNDNSAKSAAEVFRPY  240
 241 WKLNKQTLKTHLDDVQLDLPEFLFITALIYFDDGLLDQNEECIEVCKQMKAKIIEELTDY  300
 301 EKNVRINEDHSYRVGQIIMVLHGIQRTMNMIHETKEISLVYNVYDMHSSIFGNMAE
Interface Residues: 18, 19, 21, 22, 28, 29, 31, 32, 35, 36, 60, 81, 83, 85, 86, 88, 89
3D-footprint Homologues: 6fbq_A, 6l6q_B, 7wnh_D, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 7xvn_C, 4iqr_B, 2han_A, 1hcq_E, 8cef_H, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 8hbm_B, 2nll_B, 1lat_A, 7xv6_B, 4hn5_B, 8rm6_A, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A
Binding Motifs: M1425_1.02 wkyGTrryyw
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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