Transcription Factor
| Accessions: | GATA3 (HT-SELEX2 May2017) |
| Names: | ENSG00000107485, GATA3 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: Znf_GATA experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: Znf_GATA experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3 |
| Length: | 444 |
| Pfam Domains: | 264-297 GATA zinc finger 318-350 GATA zinc finger |
| Sequence: (in bold interface residues) | 1 MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFNIDGQGNHV 60 61 PPYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKT 120 121 SIHHGSPGPLSVYPPASSSSLSGGHASPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDE 180 181 KECLKYQVPLPDSMKLESSHSRGSMTALGGASSSTHHPITTYPPYVPEYSSGLFPPSSLL 240 241 GGSPTGFGCKSRPKARSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRP 300 301 LIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKE 360 361 GIQTRNRKMSSKSKKCKKVHDSLEDFPKNSSFNPAALSRHMSSLSHISPFSHSSHMLTTP 420 421 TPMHPPSSLSFGPHHPSSMVTAMG |
| Interface Residues: | 107, 108, 273, 274, 276, 286, 290, 327, 328, 330, 340, 344, 345, 348, 365, 367, 368 |
| 3D-footprint Homologues: | 2fr4_L, 3vd6_C, 4hc9_A, 3dfx_B, 1gat_A, 4gat_A |
| Binding Motifs: | GATA3_3 mGATAAcGATCw GATA3_4 mGATAAsATCw GATA3_methyl_1 wGATAAcGATCw GATA3_methyl_2 WGATAASATCw |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.