Transcription Factor
Accessions: | 1egw_A (3D-footprint 20231221) |
Names: | MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A, MEF2A_HUMAN, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1 |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | Q02078 |
Length: | 71 |
Pfam Domains: | 9-58 SRF-type transcription factor (DNA-binding and dimerisation domain) |
Sequence: (in bold interface residues) | 1 GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTD 60 61 MDKVLLKYTEY |
Interface Residues: | 2, 3, 14, 17, 18, 22, 56, 67 |
3D-footprint Homologues: | 7x1n_C, 1hbx_A, 1n6j_A, 1c7u_A, 1mnm_A, 7yq3_E |
Binding Motifs: | 1egw_AB CTannnnTAg |
Publications: | Santelli E, Richmond T.J. Crystal structure of MEF2A core bound to DNA at 1.5 A resolution. Journal of molecular biology 297:437-49 (2000). [Pubmed] |
Related annotations: | PaperBLAST |
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