Transcription Factor
| Accessions: | UP00456A (UniPROBE 20160601) |
| Names: | Gcr1, GlyColysis Regulation, LPF10 |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Description: | GlyColysis Regulation : Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p |
| Length: | 784 |
| Pfam Domains: | 636-703 Transcriptional activator of glycolytic enzymes |
| Sequence: (in bold interface residues) | 1 MVCTSTSSNFYSIAQYILQSYFKVNVDSLNSLKLVDLIVDQTYPDSLTLRKLNEGATGQP 60 61 YDYFNTVSRDADISKCPIFALTIFFVIRWSHPNPPISIENFTTVPLLDSNFISLNSNPLL 120 121 YIQNQNPNSNSSVKVSRSQTFEPSKELIDLVFPWLSYLKQDMLLIDRTNYKLYSLCELFE 180 181 FMGRVAIQDLRYLSQHPLLLPNIVTFISKFIPELFQNEEFKGIGSIKNSNNNALNNVTGI 240 241 TQFLNPSTEEVSQKVDSYFMELSKKLTTENIRLSQEITQLKADMNSVGNVCNQILLLQRQ 300 301 LLSGNQAIGSKSENIVSSTGGGILILDKNSINSNVLSNLVQSIDPNHSKPNGQAQTHQRG 360 361 PKGQSHAQVQSTNSPALAPINMFPSLSNSIQPMLGTLAPQPQDIVQKRKLPLPGSIASAA 420 421 TGSPFSPSPVGESPYSKRFKLDDKPTPSQTALDSLLTKSISSPRLPLSTLANTAVTESFR 480 481 SPQQFQHSPDFVVGGSSSSTTENNSKKVNEDSPSSSSKLAERPRLPNNDSTTSMPESPTE 540 541 VAGDDVDREKPPESSKSEPNDNSPESKDPEKNGKNSNPLGTDADKPVPISNIHNSTEAAN 600 601 SSGTVTKTAPSFPQSSSKFEIINKKDTKAGPNEAIKYKLSRENKTIWDLYAEWYIGLNGK 660 661 SSIKKLIENYGWRRWKVSEDSHFFPTRRIIMDYIETECDRGIKLGRFTNPQQPREDIRKI 720 721 LVGDLEKFRINNGLTLNSLSLYFRNLTKNNKEICIFENFKNWNVRSMTEEEKLKYCKRRH 780 781 NTPS |
| Interface Residues: | 737, 740, 744, 745 |
| 3D-footprint Homologues: | 2a66_A |
| Binding Motifs: | UP00456A_1 gkwsarwAswrGAaGCysgtwaT |
| Binding Sites: | ACTGGAAG AGCATCCT AGCTTCCT AGGAAGCC AGGAATCC AGGATGCC CAGCGTCC CGGATTCC CGGCTTCC GAGCTTCC GCTTCCTA GGAAGCCA GGAAGCCC GGAATCCA GGAATCCC GGATGCCC GGATTCCA GGCATCCA GGCTTCCA GGGCGCCC |
| Publications: | Gordân R, Murphy KF, McCord RP, Zhu C, Vedenko A, Bulyk ML. Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. Genome Biol : (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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