Transcription Factor

Accessions: T099472_1.02 (CISBP 1.02), Q9W064 (JASPAR 2024)
Names: CG42234, T099472_1.02;, Q9W064_DROME
Organisms: Drosophila melanogaster
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9W064
Notes: experiment type:PBM, family:Homeodomain
Length: 741
Pfam Domains: 437-491 Homeobox domain
Sequence:
(in bold interface residues)
1 MSTAFLVDSLLHAQQTYTESQLKSSLSEMLLSRRSATGTDAADPADQPTESCGCSKLRGY 60
61 KCDKCREIRAESVESIEEMDEDDGSSSADEIVADIGSVEGEEPHMDLDEELEEELADVDE 120
121 PVSIKLPKVEPKETSMPTVGNTILKDTNSKPILKFSVSAILGDTREGVRVRNEFMQPQHI 180
181 WPYLQQNFMQQHSHQYQQHHQQQQPHSHPQHQPLAVPGHQHSHPHSHHHHHHHPGAGHAH 240
241 FPHPAFLTHQLPPHQHHQQQQHVQQQHPGNSCQPQTASSSSSPGSTISDSDNNHGASTAN 300
301 GNGSGTGNSGQDARPHELANSNPDEDSSASRRLTQDKQQQQQLLGAGGTGGGGGGGHGHG 360
361 HPTPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHLHSLLAHCRNPYMSVGAQVFPLPPGQG 420
421 FPWAHSTRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKI 480
481 WFQNRRMKWRNSKERELLASGGSRDQTLPNKNNPNPDLSDAKCDRPLTPLSPSLLSPNGS 540
541 ATPPPPGAVAKDEPPTAAVTPKSPQSVSSRSSPSVGYGLQISSPPPLLTSLKMGDQSASA 600
601 TPTPLPGTTVSSAAASPPGVTASEFQAKINAEMQKQLVAADLKFKLENSIQEAKQRRFEQ 660
661 LQQQLHHSPHFSAMREVELAAAAAAAQLHHHHQQQQQQQQQQHAQQQHAQQQHQGGSEFM 720
721 KLYYDDYDDSNSDSDEEISVT
Interface Residues: 428, 433, 435, 436, 437, 438, 476, 477, 479, 480, 483, 484, 487, 488, 490, 491, 496
3D-footprint Homologues: 1puf_A, 1zq3_P, 2lkx_A, 5zfz_A, 3d1n_M, 1nk2_P, 2ld5_A, 1fjl_B, 6es3_K, 4xrs_G, 3cmy_A, 2hdd_A, 1b72_A, 3rkq_B, 2r5y_A, 1ig7_A, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 2d5v_B, 1jgg_B, 7psx_B, 3l1p_A, 6a8r_A, 3a01_E, 2h1k_B, 7q3o_C, 1au7_A, 5jlw_D, 3lnq_A, 7xrc_C, 2xsd_C, 1e3o_C, 1le8_A, 1puf_B, 1o4x_A, 8g87_X, 1du0_A, 5hod_A, 4qtr_D, 6m3d_C
Binding Motifs: MA0174.1 TTwATkA
M1106_1.02 ATTAATTA
Binding Sites: MA0174.1.10
MA0174.1.1
MA0174.1.11
MA0174.1.12 / MA0174.1.13
MA0174.1.14
MA0174.1.15
MA0174.1.16
MA0174.1.17
MA0174.1.18
MA0174.1.19
MA0174.1.2
MA0174.1.20
MA0174.1.3
MA0174.1.4
MA0174.1.5
MA0174.1.6
MA0174.1.7
MA0174.1.8
MA0174.1.9
Publications: Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.