Transcription Factor
| Accessions: | Q16676 (JASPAR 2024) |
| Names: | Forkhead box protein D1, Forkhead-related protein FKHL8, Forkhead-related transcription factor 4, FOXD1_HUMAN, FREAC-4 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q16676 |
| Length: | 465 |
| Pfam Domains: | 125-220 Fork head domain |
| Sequence: (in bold interface residues) | 1 MTLSTEMSDASGLAEETDIDVVGEGEDEEDEEEEDDDEGGGGGPRLAVPAQRRRRRRSYA 60 61 GEDELEDLEEEEDDDDILLAPPAGGSPAPPGPAPAAGAGAGGGGGGGGAGGGGSAGSGAK 120 121 NPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLN 180 181 DCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLLPPNAAAAESLLLR 240 241 GAGAAGGAGDPAAAAALFPPAPPPPPHAYGYGPYGCGYGLQLPPYAPPSALFAAAAAAAA 300 301 AAAFHPHSPPPPPPPHGAAAELARTAFGYRPHPLGAALPGPLPASAAKAGGPGASALARS 360 361 PFSIESIIGGSLGPAAAAAAAAQAAAAAQASPSPSPVAAPPAPGSSGGGCAAQAAVGPAA 420 421 ALTRSLVAAAAAAASSVSSSAALGTLHQGTALSSVENFTARISNC |
| Interface Residues: | 168, 170, 171, 172, 174, 175, 176, 178, 179, 188, 195, 217, 220 |
| 3D-footprint Homologues: | 7vox_H, 2hdc_A, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 3l2c_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 3qrf_G |
| Binding Motifs: | MA0031.1 GTAAACAw MA0031.2 GTAAACA |
| Binding Sites: | MA0031.1.1 MA0031.1.10 MA0031.1.11 MA0031.1.12 MA0031.1.13 MA0031.1.14 MA0031.1.15 MA0031.1.16 MA0031.1.17 MA0031.1.18 MA0031.1.19 MA0031.1.2 MA0031.1.20 MA0031.1.3 MA0031.1.4 MA0031.1.5 MA0031.1.6 MA0031.1.7 MA0031.1.8 MA0031.1.9 MA0031.2.11 / MA0031.2.3 MA0031.2.1 MA0031.2.10 MA0031.2.12 MA0031.2.13 MA0031.2.14 MA0031.2.15 MA0031.2.16 MA0031.2.17 MA0031.2.18 MA0031.2.19 MA0031.2.2 MA0031.2.20 MA0031.2.4 MA0031.2.5 MA0031.2.6 MA0031.2.7 MA0031.2.8 MA0031.2.9 |
| Publications: | Pierrou S., Hellqvist M., Samuelsson L., Enerbaeck S., Carlsson P. Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending. EMBO J. 13:5002-5012 (1994). [Pubmed] |
| Related annotations: | PaperBLAST |
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