Transcription Factor
Accessions: | UP00067A (UniPROBE 20160601) |
Names: | 3000002B05, AI451430, Lef-1, Lef1, lymphoid enhancer binding factor 1, lymphoid enhancer factor 1, Lymphoid enhancer-binding factor 1 |
Organisms: | Mus musculus |
Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
Uniprot: | P27782 |
Description: | lymphoid enhancer binding factor 1 |
Length: | 101 |
Pfam Domains: | 12-75 Domain of unknown function (DUF1898) 17-85 HMG (high mobility group) box |
Sequence: (in bold interface residues) | 1 KPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSR 60 61 EEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKL |
Interface Residues: | 19, 22, 24, 25, 28, 32, 43, 44, 45, 48, 86, 88, 90, 93, 95, 96, 97, 100 |
3D-footprint Homologues: | 2lef_A, 4y60_C, 1o4x_B, 3f27_D, 6jrp_D, 1qrv_A, 3u2b_C, 7m5w_A, 2gzk_A, 4s2q_D, 1j5n_A, 1hry_A |
Binding Motifs: | UP00067A_1 rrwycCTTTGATstwwm UP00067A_2 swrsATCAATCrctww |
Binding Sites: | AATCAAAG ACATCAAA ACTTCAAA ACTTTGAT AGATCAAA AGATCAAT ATCAAAAG ATCAAAGA ATCAAAGC ATCAAAGG CATCAAAG CCTTTGAA CTTCAAAG CTTTGAAC CTTTGATA GATCAAAA GCCTTTGA GGATCAAA TGATCAAA CTTTCATC |
Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.