Transcription Factor

Accessions: 1d5y_A (3D-footprint 20231221), 1d5y_B (3D-footprint 20231221), 1d5y_C (3D-footprint 20231221), 1d5y_D (3D-footprint 20231221)
Names: ROB TRANSCRIPTION FACTOR, ROB_ECOLI
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0ACI0
Length: 288
Pfam Domains: 25-103 Helix-turn-helix domain
67-103 Bacterial regulatory helix-turn-helix proteins, AraC family
125-282 GyrI-like small molecule binding domain
Sequence:
(in bold interface residues)
1 QAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKS 60
61 AVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPALYRRSPEWSAFGIRPPLRLGE 120
121 FTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMRYQFWHDFLGNAPTIPPVLYGLN 180
181 ETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVMLQGGEYVMFTYEGLGTGVQEFILT 240
241 VYGTCMPMLNLTRRKGQDIERYYPAEDDRPINLRCELLIPIRRKLAAA
Interface Residues: 32, 33, 34, 35, 37, 38, 41, 49, 83, 84, 87, 88, 92
3D-footprint Homologues: 3w6v_A, 7vwz_G, 1zgw_A, 1xs9_A
Binding Motifs: 1d5y_A gTGCtg
1d5y_AB caGCAc
1d5y_CD caGCAC
Binding Sites: 1d5y_M / 1d5y_O
1d5y_N / 1d5y_P
Publications: Kwon HJ., Bennik MH., Demple B., Ellenberger T. Crystal structure of the Escherichia coli Rob transcription factor in complex with DNA. Nat Struct Biol. 7(5):424-30 (2000). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.