Transcription Factor
| Accessions: | SP4 (SMILE-seq 1.0) |
| Names: | SP4, SP4_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | SMILE-seq 1.0 1 1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed] |
| Uniprot: | Q62445 |
| Length: | 779 |
| Pfam Domains: | 643-667 Zinc finger, C2H2 type 643-667 C2H2-type zinc finger 659-686 Zinc-finger double domain 673-697 C2H2-type zinc finger 673-697 Zinc finger, C2H2 type 690-712 Zinc-finger double domain 703-725 C2H2-type zinc finger 703-725 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MSDQKKEEEEEAAAAMATEGGKTSEPENNNKKPKTSGSQDSQPSPLALLAATCSKIGTPG 60 61 ENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPPASKENNVSQPAS 120 121 SSSSSSSSNNGSSSPTKTKSGNPSTPNQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQIN 180 181 PTSSSSLQDLQGQIHLISAGNNQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIPLQ 240 241 LQTLPGTQAQVVTTLPINIGGVTLALPVINNVTAGGGTGQVGQPTTTTDSGTSNGNQLVS 300 301 TPTTSTAPASTMPESPSSSTTCTTTASTTLTSSDTLVSSADTGQYASTSASSSERTIEEP 360 361 QTPAATESEAQSSSQLQSNGIQNAQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPP 420 421 QSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSLSN 480 481 LQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQTVSVANLG 540 541 AAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQVH 600 601 LQQGQQTSDAEVQPGKRLRRVACSCPNCREGEGSSEPGKKKQHVCHIEGCGKVYGKTSHL 660 661 RAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSK 720 721 HVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEE |
| Interface Residues: | 639, 655, 656, 657, 658, 659, 661, 662, 664, 665, 668, 685, 686, 687, 688, 689, 691, 692, 693, 696, 713, 714, 715, 716, 717, 718, 719, 720, 721, 724 |
| 3D-footprint Homologues: | 5yel_A, 1tf3_A, 7n5w_A, 6jnm_A, 6ml4_A, 8cuc_F, 5kkq_D, 8gn3_A, 4x9j_A, 2gli_A, 5kl3_A, 1tf6_A, 5ei9_F, 1g2f_F, 7ysf_A, 1ubd_C, 6blw_A, 5k5i_A, 2kmk_A, 1llm_D, 6u9q_A, 8ssu_A, 8h9h_G, 5v3j_F, 6e94_A, 2lt7_A, 7y3m_I, 6a57_A, 2jpa_A, 8ssq_A, 7w1m_H, 7y3l_A, 3uk3_C, 1f2i_J, 2wbs_A, 7txc_E, 2drp_D, 4m9v_C, 5yj3_D |
| Binding Motifs: | SP4 wrkGGGCGkggCy |
| Publications: | Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed] |
| Related annotations: | PaperBLAST |
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