Transcription Factor
| Accessions: | UP00300A (UniPROBE 20160601) |
| Names: | Cha4, CHA4 activatory protein, L8004.8, SIL2, SIL3, YLR098C |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P43634 |
| Description: | DNA binding transcriptional activator, mediates serine/threonine activation of the catabolic L-serine (L-threonine) deaminase (CHA1); Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear clu... |
| Length: | 128 |
| Pfam Domains: | 42-75 Fungal Zn(2)-Cys(6) binuclear cluster domain |
| Sequence: (in bold interface residues) | 1 MLEPSPPPLTTTVTPSLPSSLKKSVTDNDQNNNNVPRKRKLACQNCRRRRRKCNMEKPCS 60 61 NCIKFRTECVFTQQDLRNKRYSTTYVEALQSQIRSLKEQLQILSSSSSTIASNALSSLKN 120 121 NSDHGDAP |
| Interface Residues: | 37, 47, 49, 50, 51, 52, 64, 65, 77, 79, 80, 101, 102, 104 |
| 3D-footprint Homologues: | 1f5e_P, 1pyi_A, 2er8_C, 6o19_A, 7uik_T, 1zme_D, 6gys_C, 1d66_B, 3coq_A, 6dww_A, 6xg8_A |
| Binding Motifs: | UP00300A_1 skgkgwAwyTCCGCCbshkks |
| Binding Sites: | AACTCCGC AATTCCGC ACTCCGCC AGCGGAGA AGGCGGAG ATATCCGC ATCTCCGC ATTTCCGC CCGGCGGA CGGAAATA CGGCGGAA CGGCGGAG CGGGCGGA CTCCGCCC GGCGGAAA GGCGGAGA GGGCGGAA TATCCGCA GGCGGGAA GGGGCGGA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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