Transcription Factor
| Accessions: | UP00272A (UniPROBE 20160601) |
| Names: | 26S proteasome regulatory subunit RPN4, D2840, Nuclear protein SON1, Rpn4, UB fusion degradation protein 5, UFD5, YDL020C |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q03465 |
| Description: | Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally reg... |
| Length: | 531 |
| Sequence: (in bold interface residues) | 1 MASTELSLKRTLTDILEDELYHTNPGHSQFTSHYQNYHPNASITPYKLVNKNKENNTFTW 60 61 NHSLQHQNESSAASIPPQQTYHFPIFNKYADPTLTTTTSFTTSEATANDRQINNVHLIPN 120 121 EIKGASETPLQKTVNLKNIMKVSDPYVPTRNTFNYDVKISNDFFDNGDNLYGNDEEVLFY 180 181 EDNYNPKMQWSLQDNSAAINNEDARAIFNNEFDSDDDDISDDEEDEIEENYLQQEQHQEE 240 241 PLLSLDVTPISMFGSDQKTGRAKSSSHLFNEYSYVDSNMDSISSVVSEDLLDERGHEKIE 300 301 DEDEDNDLDEDDIYDISLLKNRRKQSFVLNKNTIDFERFPSPSTSANVPSTATTGKRKPA 360 361 KSSSNRSCVSNSNENGTLERIKKPTSAVVSSNASRRKLINYTKKHLSSHSSTNSNSKPST 420 421 ASPSAHTSSSDGNNEIFTCQIMNLITNEPCGAQFSRSYDLTRHQNTIHAKRKIVFRCSEC 480 481 IKILGSEGYQKTFSRLDALTRHIKSKHEDLSLEQRQEVTKFAKANIGYVMG |
| Interface Residues: | 455, 456, 457, 458, 459, 461, 462, 495, 496, 497, 498, 500, 501 |
| 3D-footprint Homologues: | 1tf3_A, 2drp_D, 2wbs_A, 1f2i_J, 6u9q_A, 4x9j_A, 1mey_C, 2i13_A, 5kl3_A, 7ysf_A, 2jpa_A, 6blw_A, 2gli_A, 7eyi_G |
| Binding Motifs: | UP00272A_1 wbkwaaCGCCACCCkaawcs |
| Binding Sites: | AAAAAATA AACGCCAC AATTTTCA ACGCCACC AGAGGGGG ATTTTTTC CGCCACCC CGCCACCG CGCCCCCC GCGCCACC GGGGGAAA GGTGGCAA GGTGGCGA GTGGCAAA TTAATTAA AGGTGGCG ATATAGAA CAGAAAAA CCGCCACC GGGGGCAA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.