Transcription Factor

Accessions: UP00272A (UniPROBE 20160601)
Names: 26S proteasome regulatory subunit RPN4, D2840, Nuclear protein SON1, Rpn4, UB fusion degradation protein 5, UFD5, YDL020C
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q03465
Description: Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally reg...
Length: 531
Sequence:
(in bold interface residues)
1 MASTELSLKRTLTDILEDELYHTNPGHSQFTSHYQNYHPNASITPYKLVNKNKENNTFTW 60
61 NHSLQHQNESSAASIPPQQTYHFPIFNKYADPTLTTTTSFTTSEATANDRQINNVHLIPN 120
121 EIKGASETPLQKTVNLKNIMKVSDPYVPTRNTFNYDVKISNDFFDNGDNLYGNDEEVLFY 180
181 EDNYNPKMQWSLQDNSAAINNEDARAIFNNEFDSDDDDISDDEEDEIEENYLQQEQHQEE 240
241 PLLSLDVTPISMFGSDQKTGRAKSSSHLFNEYSYVDSNMDSISSVVSEDLLDERGHEKIE 300
301 DEDEDNDLDEDDIYDISLLKNRRKQSFVLNKNTIDFERFPSPSTSANVPSTATTGKRKPA 360
361 KSSSNRSCVSNSNENGTLERIKKPTSAVVSSNASRRKLINYTKKHLSSHSSTNSNSKPST 420
421 ASPSAHTSSSDGNNEIFTCQIMNLITNEPCGAQFSRSYDLTRHQNTIHAKRKIVFRCSEC 480
481 IKILGSEGYQKTFSRLDALTRHIKSKHEDLSLEQRQEVTKFAKANIGYVMG
Interface Residues: 455, 456, 457, 458, 459, 461, 462, 495, 496, 497, 498, 500, 501
3D-footprint Homologues: 1tf3_A, 5kl3_A, 7ysf_A, 2jpa_A, 6blw_A, 2drp_D, 2wbs_A, 1f2i_J, 6u9q_A, 4x9j_A, 1mey_C, 2i13_A, 2gli_A, 7eyi_G
Binding Motifs: UP00272A_1 wbkwaaCGCCACCCkaawcs
Binding Sites: AAAAAATA
AACGCCAC
AATTTTCA
ACGCCACC
AGAGGGGG
ATTTTTTC
CGCCACCC
CGCCACCG
CGCCCCCC
GCGCCACC
GGGGGAAA
GGTGGCAA
GGTGGCGA
GTGGCAAA
TTAATTAA
AGGTGGCG
ATATAGAA
CAGAAAAA
CCGCCACC
GGGGGCAA
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.