Transcription Factor

						

			
Accessions: TEF (HT-SELEX2 May2017)

			
Names: ENSG00000167074, TEF
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4
Length: 93
Pfam Domains:     22-75 Basic region leucine zipper
    23-82 bZIP transcription factor
Sequence: 
(in bold interface residues)		   1 EDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKNNVAAKRSRDARRLKENQITIRAAFLEK   60
  61 ENTALRTEVAELRKEVGKCKTIVSKYETKYGPL
Interface Residues: 22, 23, 29, 30, 33, 34, 36, 37, 38, 39, 40, 41, 43
3D-footprint Homologues: 8him_B, 2wt7_A, 1nwq_C, 6mg1_B
Binding Motifs: TEF_2 srTTACGTAAys
TEF_methyl_1 brTTAyGTAAyr
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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