Transcription Factor

Accessions: UP00345A (UniPROBE 20160601)
Names: Met32, Methionine-requiring protein 32, Transcriptional regulator MET32, YD9320A.03C, YDR253C
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q12041
Description: Zinc-finger DNA-binding protein, involved in regulating expression of the methionine biosynthetic genes, similar to Met31p
Length: 144
Pfam Domains: 51-73 Zinc finger, C2H2 type
51-73 C2H2-type zinc finger
80-100 C2H2-type zinc finger
81-99 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 KPALIPAENGVDINSQGGNIKVKKENALPKPPKSSKSKPQDRRNSTGEKRFKCAKCSLEF 60
61 SRSSDLRRHEKTHFAILPNICPQCGKGFARKDALKRHYDTLTCRRNRTKLLTAGGEGINE 120
121 LLKKVKQSNIVHRQDNNHNGSSNG
Interface Residues: 36, 37, 40, 44, 51, 61, 62, 63, 64, 65, 67, 68, 69, 71, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 100
3D-footprint Homologues: 6e94_A, 6jnm_A, 6a57_A, 7n5w_A, 5ei9_F, 8h9h_G, 7w1m_H, 2kmk_A, 1g2f_F, 8cuc_F, 1tf3_A, 7y3l_A, 5kl3_A, 2wbs_A, 1tf6_A, 6u9q_A, 5yj3_D, 2i13_A, 1llm_D, 5und_A, 3uk3_C, 1ubd_C, 6wmi_A, 5k5i_A, 2jpa_A, 8ssq_A, 1mey_C, 2drp_D, 1f2i_J, 6blw_A, 5kkq_D, 6ml4_A, 5yel_A, 4x9j_A, 8gn3_A, 5v3j_F, 4m9v_C, 2gli_A, 7y3m_I, 7ysf_A, 7eyi_G, 7txc_E, 6dnw_A
Binding Motifs: UP00345A_1 kyyyawAsTGTGGCGysbstm
Binding Sites: AAGCCACA
ACGCCACA
ACTGTGGC
AGCCACAA
AGCCACAC
AGCCACAG
AGTGTGGC
ATGTGGCG
ATTGTGGC
CAGCCACA
CCGCCACA
CGCCACAA
CGCCACAC
CGCCACAG
GACGCCAC
GAGCCACA
GCCACACC
GCCACAGC
GCGCCACA
GCCACACA
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.