Transcription Factor
| Accessions: | H2KZZ2 (JASPAR 2024) |
| Names: | H2KZZ2_CAEEL, HLH30_CAEEL |
| Organisms: | Caenorhabditis elegans |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | H2KZZ2 |
| Length: | 524 |
| Pfam Domains: | 265-317 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MIRQLNSPGGGGGLGLNNPRAQQPPGAQQQQQPQQAQQQFYDDEPYQANASQFRFGAGKS 60 61 MEQRRETGNLIPIAQRSMGSTSTPFGSAPTQSYFGGGSSGAALSSPRKMQQTHQMLFGNI 120 121 QPPRGSPPSDGSDKIHRFGESPTPGGVGGVFGTELDDLIIDELMGMEDDQRMRPGATRPM 180 181 TIGGEKTMSMARPIPGASSRAGSGHSGSPITIPNAMSNNFRQVVSSSAPTSSIDIEKMIG 240 241 AVSNGGGNSGGDNDPEDYYRDRRKKDIHNMIERRRRYNINDRIKELGQMLPKNTSEDMKL 300 301 NKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEMLARQGVQVPP 360 361 SHLPPIPKVIERPIKQEIDESPPNHTPTGSFVSSSGFLSEVTNNTAAMQITSPNDSRPNN 420 421 FMNNSAPSDSFFSVGSASPPDYRTSSGTASWKLPGSNAFSDLMMDDLNPMMNGDPLISSA 480 481 GAHPSPHFHSSQMSPDIHWDASGFSPDPINTQQSNSGHYHMDFS |
| Interface Residues: | 265, 267, 268, 269, 271, 272, 273, 275, 276, 300, 302, 304, 307, 308, 309, 312, 356 |
| 3D-footprint Homologues: | 1a0a_B, 1an4_A, 8osl_O, 6od3_F, 5gnj_I, 5v0l_A, 4h10_B, 7d8t_A, 5i50_B, 7xi3_A, 4zpk_A, 1am9_A, 7f2f_B, 5nj8_D, 3mva_O, 6g1l_A, 5eyo_A, 7ssa_L, 4h10_A, 2ypa_A, 8osl_P, 2ypa_B, 7xhv_B, 5v0l_B, 7xi3_B, 5t2n_A |
| Binding Motifs: | MA1449.1 wrTCACGTGAyw MA1449.2 TCACGTGA |
| Binding Sites: | MA1449.2.1 MA1449.2.18 / MA1449.2.9 MA1449.2.13 / MA1449.2.19 MA1449.2.15 / MA1449.2.16 / MA1449.2.3 / MA1449.2.4 / MA1449.2.5 / MA1449.2.6 / MA1449.2.7 / MA1449.2.8 MA1449.2.12 MA1449.1.1 MA1449.1.10 MA1449.1.11 MA1449.1.12 MA1449.1.13 MA1449.1.14 MA1449.1.15 MA1449.1.16 MA1449.1.17 MA1449.1.18 MA1449.1.19 MA1449.1.2 MA1449.1.20 MA1449.1.3 MA1449.1.4 MA1449.1.5 MA1449.1.6 MA1449.1.7 / MA1449.1.8 MA1449.1.9 MA1449.2.10 / MA1449.2.17 MA1449.2.2 MA1449.2.11 MA1449.2.14 / MA1449.2.20 |
| Publications: | Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.