Transcription Factor

						

			
Accessions: 2pi0_B (3D-footprint 20231221)

			
Names: Interferon regulatory factor 3, IRF-3, IRF3_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q14653
Length: 112
Pfam Domains:     7-111 Interferon regulatory factor transcription factor
Sequence: 
(in bold interface residues)		   1 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA   60
  61 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNS
Interface Residues: 40, 42, 74, 78, 79, 81, 82, 85, 86
3D-footprint Homologues: 1if1_B, 2o61_A, 2pi0_B, 2irf_L, 7oot_B
Binding Motifs: 2pi0_ABCD GGnAAACTGAAAGGGaGAnnTnAAAG
2pi0_B tTtC
Binding Sites: 2pi0_E
2pi0_F
			
Publications: Escalante C.R, Nistal-Villán E, Shen L, García-Sastre A, Aggarwal A.K. Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer. Molecular cell 26:703-16 (2007). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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