Transcription Factor

Accessions: T023841_1.02 (CISBP 1.02), T08900 (AthalianaCistrome v4_May2016), O22873 (JASPAR 2024), bZIP18 (EEADannot 2023-12-22)
Names: AT2G40620, T023841_1.02;, bZIP18, T08900;, AtbZIP18, bZIP protein 18, bZIP transcription factor 18, BZP18_ARATH
Organisms: Arabidopsis thaliana
Libraries: CISBP 1.02 1, AthalianaCistrome v4_May2016 2, JASPAR 2024 3, EEADannot 2023-12-22 4
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
4 Contreras-Moreira B, Sebastian A. FootprintDB: Analysis of Plant Cis-Regulatory Elements, Transcription Factors, and Binding Interfaces. Methods Mol Biol 1482:259-77 (2016) [Pubmed]
Notes: experiment type:PBM, family:bZIP, ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq
Length: 367
Pfam Domains: 148-197 Basic region leucine zipper
150-207 bZIP transcription factor
Sequence:
(in bold interface residues)
1 MEDPSNPQPNQSNLSQCPPLATAPTPAPVRGPYHRRAHSEVQFRLPEDLDLSEPFGGFDE 60
61 LGSEDDLFCSYMDIEKLGSGSGSASDSAGPSAPRSDNPFSAENGGAEAGNSRPRHRHSLS 120
121 VDGSSTLESIEAKKAMAPDKLAELWVVDPKRAKRIIANRQSAARSKERKARYILELERKV 180
181 QTLQTEATTLSAQLSLFQRDTTGLSSENTELKLRLQVMEQQAKLRDALNEQLKKEVERLK 240
241 FATGEVSPADAYNLGMAHMQYQQQPQQSFFQHHHQQQTDAQNLQQMTHQFHLFQPNNNQN 300
301 QSSRTNPPTAHQLMHHATSNAPAQSHSYSEAMHEDHLGRLQGLDISSCGRGSNFGRSDTV 360
361 SESSSTM
Interface Residues: 97, 112, 116, 154, 158, 161, 162, 165, 166
3D-footprint Homologues: 2xhb_A, 7x5e_F
Binding Motifs: M0262_1.02 tkmCAgctgk
M0190 wTGmCAGCTkk
M0208 amcAGCTGkCA
MA1742.1 TGmCAGCTgkt
EEAD0134 TGmCAGCTgk
EEAD0135 kmCAGGCTGkm
MA1742.2 TGmCAGCTgk
Publications: Lacroix B, Citovsky V. Characterization of VIP1 activity as a transcriptional regulator in vitro and in planta. Sci Rep : (2013;3:2440.). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.