Transcription Factor
| Accessions: | Q8NCK3 (JASPAR 2024) |
| Names: | ZN485_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8NCK3 |
| Length: | 441 |
| Pfam Domains: | 11-51 KRAB box 130-152 Zinc finger, C2H2 type 130-152 C2H2-type zinc finger 130-153 C2H2-type zinc finger 147-167 Zinc-finger double domain 157-180 C2H2-type zinc finger 158-180 Zinc finger, C2H2 type 172-194 Zinc-finger double domain 204-224 Zinc-finger double domain 213-234 C2H2-type zinc finger 229-252 Zinc-finger double domain 241-252 C2H2-type zinc finger 242-264 Zinc finger, C2H2 type 242-264 C2H2-type zinc finger 256-279 Zinc-finger double domain 270-281 C2H2-type zinc finger 270-292 Zinc finger, C2H2 type 270-292 C2H2-type zinc finger 287-308 Zinc-finger double domain 298-320 C2H2-type zinc finger 298-320 C2H2-type zinc finger 298-320 Zinc finger, C2H2 type 315-336 Zinc-finger double domain 326-348 C2H2-type zinc finger 326-349 C2H2-type zinc finger 326-348 Zinc finger, C2H2 type 344-364 Zinc-finger double domain 354-376 C2H2-type zinc finger 354-374 C2H2-type zinc finger 354-376 Zinc finger, C2H2 type 370-393 Zinc-finger double domain 382-404 Zinc finger, C2H2 type 382-404 C2H2-type zinc finger 382-404 C2H2-type zinc finger 397-419 Zinc-finger double domain 409-432 C2H2-type zinc finger 410-432 Zinc finger, C2H2 type 410-432 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MAPRAQIQGPLTFGDVAVAFTRIEWRHLDAAQRALYRDVMLENYGNLVSVGLLSSKPKLI 60 61 TQLEQGAEPWTEVREAPSGTHAVEDYWFETKMSALKQSTSEASVLGERTKSVMMEKGLDW 120 121 EGRSSTEKNYKCKECGKVFKYNSSFISHQRNHTSEKPHKCKECGIAFMNSSSLLNHHKVH 180 181 AGKQPYRCIECGKFLKKHSTFINHQRIHSREKPHKCIECGKTFRKNSILLSHQRIHTGQK 240 241 PYKCNDCGKAFAQNAALTRHERIHSGEKPFKCNKCGRAFRDNSTVLEHQKIHTGEKPYQC 300 301 NECGKAFRKSSTLISHQRMHTGEKPYHCSKCGKSFRYSSSFAGHQKTHSGNKPYQCRDCG 360 361 KAFTKSSTLTGHQRIHTGEKPYHCKKCGKAFRHSSGLVEHQRLHTGEKPYKCNECGKAFP 420 421 RSSALKQHKKIHNKERAMKCS |
| Interface Residues: | 143, 169, 171, 172, 175, 179, 183, 196, 200, 224, 225, 226, 227, 228, 230, 231, 233, 234, 235, 237, 242, 252, 253, 254, 255, 256, 258, 259, 280, 281, 282, 283, 284, 287, 290, 308, 309, 310, 311, 312, 315, 336, 337, 338, 339, 340, 341, 342, 343, 345, 364, 365, 366, 367, 368, 370, 371, 377, 391, 392, 393, 394, 395, 396, 398, 399, 400, 403, 420, 421, 422, 423, 424, 425, 426, 427, 428, 430 |
| 3D-footprint Homologues: | 7y3m_I, 7w1m_H, 3uk3_C, 8ssq_A, 8ssu_A, 5v3j_F, 1g2f_F, 5kkq_D, 1tf6_A, 6u9q_A, 2i13_A, 5yel_A, 2jpa_A, 1ubd_C, 2kmk_A, 8cuc_F, 7y3l_A, 5ei9_F, 5und_A, 6blw_A, 7txc_E, 6wmi_A, 2lt7_A, 6jnm_A, 2gli_A, 6e94_A, 7n5w_A, 2drp_D, 5k5i_A, 6ml4_A, 7eyi_G, 8h9h_G, 7ysf_A, 1tf3_A, 1mey_C, 1f2i_J, 4x9j_A, 5kl3_A, 6a57_A, 8gn3_A, 1llm_D, 2wbs_A, 4m9v_C, 5yj3_D |
| Binding Motifs: | UN0620.1 wwtrGAGATATAyrr UN0620.2 trGAGATATAy |
| Binding Sites: | UN0620.1.1 / UN0620.1.3 UN0620.1.10 UN0620.1.11 UN0620.1.12 UN0620.1.13 UN0620.1.14 UN0620.1.15 UN0620.1.16 UN0620.1.17 UN0620.1.18 UN0620.1.19 UN0620.1.12 / UN0620.1.2 UN0620.1.20 UN0620.1.3 UN0620.1.14 / UN0620.1.4 UN0620.1.18 / UN0620.1.5 UN0620.1.6 UN0620.1.7 UN0620.1.8 UN0620.1.9 UN0620.1.1 UN0620.1.10 UN0620.1.11 UN0620.1.13 UN0620.1.15 UN0620.1.16 UN0620.1.17 UN0620.1.19 UN0620.1.2 UN0620.1.20 UN0620.1.4 UN0620.1.5 UN0620.1.6 UN0620.1.7 UN0620.1.8 UN0620.1.9 UN0620.2.1 UN0620.2.10 UN0620.2.11 UN0620.2.12 UN0620.2.13 UN0620.2.14 UN0620.2.15 UN0620.2.16 UN0620.2.17 UN0620.2.18 UN0620.2.19 UN0620.2.2 UN0620.2.20 UN0620.2.3 UN0620.2.4 UN0620.2.5 UN0620.2.6 UN0620.2.7 UN0620.2.8 UN0620.2.9 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.