Transcription Factor

Accessions: Q969W8 (JASPAR 2024)
Names: ZN566_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q969W8
Length: 418
Pfam Domains: 6-46 KRAB box
188-210 Zinc-finger double domain
198-210 C2H2-type zinc finger
199-221 C2H2-type zinc finger
199-221 Zinc finger, C2H2 type
214-236 Zinc-finger double domain
226-245 C2H2-type zinc finger
241-266 Zinc-finger double domain
254-275 C2H2-type zinc finger
255-277 C2H2-type zinc finger
255-277 Zinc finger, C2H2 type
269-294 Zinc-finger double domain
282-303 C2H2-type zinc finger
283-305 C2H2-type zinc finger
283-305 Zinc finger, C2H2 type
297-321 Zinc-finger double domain
310-331 C2H2-type zinc finger
311-333 C2H2-type zinc finger
311-333 Zinc finger, C2H2 type
326-349 Zinc-finger double domain
338-359 C2H2-type zinc finger
339-361 Zinc finger, C2H2 type
339-361 C2H2-type zinc finger
353-377 Zinc-finger double domain
366-385 C2H2-type zinc finger
367-387 C2H2-type zinc finger
367-389 Zinc finger, C2H2 type
384-406 Zinc-finger double domain
Sequence:
(in bold interface residues)
1 MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNVISYLEQ 60
61 GKEPWLADRELTRGQWPVLESRCETKKLFLKKEIYEIESTQWEIMEKLTRRDFQCSSFRD 120
121 DWECNRQFKKELGSQGGHFNQLVFTHEDLPTLSHHPSFTLQQIINSKKKFCASKEYRKTF 180
181 RHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTGKKPFECKECGKTFICGS 240
241 DLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPYECKECGKAFSSGSNFTQ 300
301 HQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRI 360
361 HTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKNFNYDPQLIQHQNLYW
Interface Residues: 184, 188, 209, 210, 212, 213, 216, 220, 226, 228, 238, 239, 240, 241, 243, 244, 245, 248, 249, 250, 252, 254, 255, 265, 266, 267, 268, 269, 270, 271, 272, 273, 275, 293, 294, 295, 296, 297, 299, 300, 302, 303, 304, 306, 311, 321, 322, 323, 324, 325, 327, 328, 349, 350, 351, 352, 353, 355, 356, 362, 376, 378, 379, 380, 381, 382, 383, 384, 388, 405, 406, 407, 408, 409, 412
3D-footprint Homologues: 7w1m_H, 8ssu_A, 1tf6_A, 6wmi_A, 8ssq_A, 1i3j_A, 5und_A, 2gli_A, 5v3j_F, 7txc_E, 4m9v_C, 2lt7_A, 8cuc_F, 7y3l_A, 7n5w_A, 6ml4_A, 4x9j_A, 5ei9_F, 1mey_C, 2drp_D, 7eyi_G, 8h9h_G, 2i13_A, 6e94_A, 5yel_A, 6jnm_A, 5k5l_F, 1llm_D, 6blw_A, 5kkq_D, 6u9q_A, 1g2f_F, 5k5i_A, 7ysf_A, 6a57_A, 2jpa_A, 1ubd_C, 2kmk_A, 1tf3_A, 2wbs_A, 5kl3_A, 5yj3_D, 3uk3_C, 8gn3_A, 1f2i_J, 7y3m_I
Binding Motifs: UN0632.1 GCkGsAmrGGAgsCgGgs
UN0632.2 GCkGsAmrGGAgsCgGg
Related annotations: PaperBLAST

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