Transcription Factor
| Accessions: | P22561 (JASPAR 2024) |
| Names: | WT1_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 449 |
| Pfam Domains: | 1-321 Wilm's tumour protein 339-365 Zinc-finger double domain 353-377 Zinc finger, C2H2 type 353-377 C2H2-type zinc finger 370-393 Zinc-finger double domain 383-405 Zinc finger, C2H2 type 383-405 C2H2-type zinc finger 397-426 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MGSDVRDLNALLPAVSSLGGGGGGCGLPVSGARQWAPVLDFAPPGASAYGSLGGPAPPPA 60 61 PPPPPPPPHSFIKQEPSWGGAEPHEEQCLSAFTLHFSGQFTGTAGACRYGPFGPPPPSQA 120 121 SSGQARMFPNAPYLPSCLESQPTIRNQGYSTVTFDGAPSYGHTPSHHAAQFPNHSFKHED 180 181 PMGQQGSLGEQQYSVPPPVYGCHTPTDSCTGSQALLLRTPYSSDNLYQMTSQLECMTWNQ 240 241 MNLGATLKGMAAGSSSSVKWTEGQSNHGIGYESENHTAPILCGAQYRIHTHGVFRGIQDV 300 301 RRVSGVAPTLVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDC 360 361 ERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGKTSEKPFSCRWHS 420 421 CQKKFARSDELVRHHNMHQRNMTKLHVAL |
| Interface Residues: | 264, 310, 312, 335, 336, 337, 338, 339, 341, 342, 344, 345, 348, 365, 366, 367, 368, 369, 371, 372, 376, 393, 394, 395, 396, 397, 399, 400, 427, 428, 429, 430, 432, 433 |
| 3D-footprint Homologues: | 7abs_A, 7w1m_H, 5v3j_F, 1tf3_A, 7n5w_A, 8ssu_A, 2kmk_A, 6u9q_A, 8ssq_A, 2gli_A, 8h9h_G, 2lt7_A, 1tf6_A, 7y3m_I, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 8cuc_F, 7y3l_A, 7txc_E, 2drp_D, 8gn3_A |
| Binding Motifs: | MA1627.1 cycCTCCCCCACmc MA1627.2 cCTCCCCCAC |
| Binding Sites: | MA1627.1.1 MA1627.1.10 / MA1627.1.6 MA1627.1.11 MA1627.1.12 MA1627.1.13 / MA1627.1.7 MA1627.1.14 / MA1627.1.8 MA1627.1.15 / MA1627.1.9 MA1627.1.16 MA1627.1.10 / MA1627.1.17 MA1627.1.11 / MA1627.1.18 MA1627.1.12 / MA1627.1.19 MA1627.1.1 / MA1627.1.2 MA1627.1.20 MA1627.1.2 / MA1627.1.3 MA1627.1.3 / MA1627.1.4 MA1627.1.4 / MA1627.1.5 MA1627.1.6 MA1627.1.5 / MA1627.1.7 MA1627.1.8 MA1627.1.9 MA1627.1.13 MA1627.1.14 MA1627.1.15 MA1627.1.16 MA1627.1.17 MA1627.1.18 MA1627.1.19 MA1627.1.20 MA1627.2.20 MA1627.2.1 MA1627.2.10 MA1627.2.11 MA1627.2.12 MA1627.2.13 MA1627.2.14 MA1627.2.15 MA1627.2.16 / MA1627.2.4 MA1627.2.17 MA1627.2.18 MA1627.2.19 MA1627.2.2 / MA1627.2.6 MA1627.2.3 MA1627.2.5 MA1627.2.7 MA1627.2.8 MA1627.2.9 |
| Publications: | Hamilton TB, Barilla KC, Romaniuk PJ. High affinity binding sites for the Wilms' tumour suppressor protein WT1. Nucleic Acids Res 23:277-84 (1995). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.