Transcription Factor

						

			
Accessions: 2c6y_A (3D-footprint 20231221)

			
Names: FORKHEAD BOX PROTEIN K2, FOXK2_HUMAN, G/T-mismatch specific binding protein, Interleukin enhancer-binding factor 1, nGTBP
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q01167
Length: 98
Pfam Domains:      3-97 Fork head domain
Sequence: 
(in bold interface residues)		   1 DSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRY   60
  61 FIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPR
Interface Residues: 43, 46, 48, 49, 50, 52, 53, 54, 56, 57, 66, 73, 98
3D-footprint Homologues: 3l2c_A, 7vox_H, 2hdc_A, 7tdx_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 3qrf_G
Binding Motifs: 2c6y_A TanTGTTTA
2c6y_AB TAAACAATACA
Binding Sites: 2c6y_C
2c6y_D
			
Publications: Tsai K.L, Huang C.Y, Chang C.H, Sun Y.J, Chuang W.J, Hsiao C.D. Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins. The Journal of biological chemistry 281:17400-9 (2006). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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