Transcription Factor

Accessions: Q01664 (JASPAR 2024)
Names: Activating enhancer-binding protein 4, bHLHc41, Class C basic helix-loop-helix protein 41, TFAP4_HUMAN, Transcription factor AP-4
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q01664
Length:
Binding Motifs: MA0691.1 AwCAGCTGwT
MA1966.1 rsCGGAwgCAGsTGgk
MA1967.1 acCGGAAACAGCTGwy
MA1570.1 ahCAyrTGkt
MA1966.2 sCGGAwgCAGsTG
MA1967.2 acCGGAAACAGCTG
Publications: Jung P, Menssen A, Mayr D, Hermeking H. AP4 encodes a c-MYC-inducible repressor of p21. Proc Natl Acad Sci U S A 105:15046-51 (2008). [Pubmed]

Badinga L, Song S, Simmen RC, Simmen FA. A distal regulatory region of the insulin-like growth factor binding protein-2 (IGFBP-2) gene interacts with the basic helix-loop-helix transcription factor, AP-4. Endocrine 8:281-9 (1998). [Pubmed]

Guturu H, Doxey AC, Wenger AM, Bejerano G. Structure-aided prediction of mammalian transcription factor complexes in conserved non-coding elements. Philos Trans R Soc Lond B Biol Sci 368:20130029 (2013). [Pubmed]
Related annotations: PaperBLAST

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