Transcription Factor

Accessions: 1xbr_A (3D-footprint 20231221)
Names: Brachyury protein, Protein T, T PROTEIN, T-box transcription factor T, TBXT_XENLA, xBRA
Organisms: Xenopus laevis
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P24781
Length: 184
Pfam Domains: 3-179 T-box
Sequence:
(in bold interface residues)
1 ELKVSLEERDLWTRFKELTNEMIVTKNGRRMFPVLKVSMSGLDPNAMYTVLLDFVAADNH 60
61 RWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKDPVSFSKVKLTNKMNGGGQIML 120
121 NSLHKYEPRIHIVRVGGTQRMITSHSFPETQFIAVTAYQNEEITALKIKHNPFAKAFLDA 180
181 KERN
Interface Residues: 29, 156, 157, 173, 176, 177
3D-footprint Homologues: 4a04_B, 1h6f_B, 5flv_I, 1xbr_B, 6f59_B, 2x6v_A
Binding Motifs: 1xbr_AB TnnnCACnnAggTGnnnA
Publications: Müller C.W, Herrmann B.G. Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor. Nature 389:884-8 (1997). [Pubmed]
Related annotations: PaperBLAST

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