Transcription Factor
Accessions: | 1cf7_A (3D-footprint 20231221) |
Names: | E2F4_HUMAN, TRANSCRIPTION FACTOR E2F-4, Transcription factor E2F4 |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | Q16254 |
Length: | 67 |
Pfam Domains: | 2-67 E2F/DP family winged-helix DNA-binding domain |
Sequence: (in bold interface residues) | 1 SRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQKRRIYDITNVLEGIGLIEKKS 60 61 KNSIQWK |
Interface Residues: | 2, 39, 40, 41, 42, 44 |
3D-footprint Homologues: | 4yo2_A, 1cf7_A, 1cf7_B |
Binding Motifs: | 1cf7_A tTcGCGCG 1cf7_AB TCGCGCG |
Binding Sites: | 1cf7_C 1cf7_D |
Publications: | Zheng N., Fraenkel E., Pabo C. O., Pavletich N. P. Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes Dev. 13:666-674 (1999). [Pubmed] |
Related annotations: | PaperBLAST |
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