Transcription Factor

Accessions: T061409_1.02 (CISBP 1.02)
Names: egl-43, T061409_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 322
Pfam Domains: 223-245 C2H2-type zinc finger
223-245 Zinc finger, C2H2 type
237-261 Zinc-finger double domain
251-274 C2H2-type zinc finger
251-274 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MPSQAALTKHRPVCEMTALYKPLMAQLAGLSGAGGLGSVPYWPHILQMATQAPHFPLAFL 60
61 AANPEAYKLMQQTTCASPDAECSSGHASESSPTTTEPVDLTATPKPPSTSEMETTSKSDD 120
121 GEDRDSIGDSGNDDDDDSEAGVLDESSTTTSTKKRPTSHTISDILAAPQLGAQALNSTFL 180
181 GMLQRSLNYNPAVPSPHSFLRAMSGAKASSSPSSSSGSGKDRYTCKFCQKVFPRSANLTR 240
241 HLRTHTGEQPYKCQYCERSFSISSNLQRHVRNIHNKPNTSLTPHNHHRQRSLHNSTSTST 300
301 TTTTVHHPLLHLPGTSVPVPKV
Interface Residues: 214, 215, 218, 233, 234, 235, 236, 237, 239, 240, 241, 261, 262, 263, 264, 265, 266, 267, 268, 269, 272, 287, 289, 290
3D-footprint Homologues: 2jpa_A, 3uk3_C, 2kmk_A, 8cuc_F, 7y3l_A, 1g2f_F, 5kl3_A, 1ubd_C, 8gn3_A, 7txc_E, 6a57_A, 5k5i_A, 1llm_D, 7ysf_A, 6ml4_A, 5v3j_F, 2drp_D, 8h9h_G, 7w1m_H, 6blw_A, 5k5l_F, 2lt7_A, 6u9q_A, 5yel_A, 4x9j_A, 2gli_A, 8ssq_A, 1f2i_J, 5kkq_D, 2wbs_A, 7n5w_A, 5ei9_F, 6jnm_A, 4m9v_C, 1tf3_A, 6e94_A, 1tf6_A, 7y3m_I, 5yj3_D, 8gh6_A
Binding Motifs: M0489_1.02 rkGATGmghh
Related annotations: PaperBLAST

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