Transcription Factor
| Accessions: | PAX4_full (HumanTF 1.0) |
| Names: | PAX4, PAX4_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Uniprot: | O43316 |
| Notes: | Ensembl ID: ENSG00000106331; Full protein sequence; TF family: PAX+Homeodomain; Clone source: Megaman |
| Length: | 349 |
| Pfam Domains: | 7-129 'Paired box' domain 172-227 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MHQDGISSMNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGR 60 61 YYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPS 120 121 VSSINRVLRALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPS 180 181 QAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGA 240 241 SQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACL 300 301 KPCWDCGSFLLPVIAPSCVDVAWPCLDASLAHHLIGGAGKATPTHFSH* |
| Interface Residues: | 18, 50, 51, 53, 55, 56, 72, 75, 78, 120, 121, 122, 123, 125, 126, 129, 169, 171, 172, 173, 174, 212, 213, 215, 216, 219, 220, 223, 224, 227 |
| 3D-footprint Homologues: | 1pdn_C, 6pax_A, 1k78_A, 1mnm_C, 1le8_B, 1k61_B, 1puf_A, 6a8r_A, 3d1n_M, 5zfz_A, 1zq3_P, 6m3d_C, 3lnq_A, 2lkx_A, 1nk2_P, 1jgg_B, 2ld5_A, 7q3o_C, 6es3_K, 5flv_I, 5zjt_E, 1au7_A, 3a01_E, 2h1k_B, 5hod_A, 1fjl_B, 1b72_A, 3cmy_A, 2hdd_A, 5jlw_D, 1ig7_A, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 2hos_A, 7psx_B, 4cyc_A, 1e3o_C, 7xrc_C, 1le8_A, 2xsd_C, 3l1p_A, 4qtr_D, 6wig_A, 8g87_X, 1du0_A, 1o4x_A, 4j19_B |
| Binding Motifs: | PAX4_full ctAATTAg |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.