Transcription Factor

Accessions: RAV1 (Athamap 20091028), T004628_1.02 (CISBP 1.02), Q9ZWM9 (JASPAR 2024), T00471 (AthalianaCistrome v4_May2016)
Names: RAV1, T004628_1.02;, AP2/ERF and B3 domain-containing transcription factor RAV1, Ethylene-responsive transcription factor RAV1, Protein RELATED TO ABI3/VP1 1, RAV1_ARATH, AT1G13260, T00471;
Organisms: Arabidopsis thaliana
Libraries: Athamap 20091028 1, CISBP 1.02 2, JASPAR 2024 3, AthalianaCistrome v4_May2016 4
1 Bulow L, Engelmann S, Schindler M, Hehl R. AthaMap, integrating transcriptional and post-transcriptional data. Nucleic acids research 37:D983-6 (2009). [Pubmed]
2 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
4 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: experiment type:PBM, family:AP2,B3, ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:RAV
Length: 344
Pfam Domains: 60-107 AP2 domain
188-291 B3 DNA binding domain
Sequence:
(in bold interface residues)
1 MESSSVDESTTSTGSICETPAITPAKKSSVGNLYRMGSGSSVVLDSENGVEAESRKLPSS 60
61 KYKGVVPQPNGRWGAQIYEKHQRVWLGTFNEEDEAARAYDVAVHRFRRRDAVTNFKDVKM 120
121 DEDEVDFLNSHSKSEIVDMLRKHTYNEELEQSKRRRNGNGNMTRTLLTSGLSNDGVSTTG 180
181 FRSAEALFEKAVTPSDVGKLNRLVIPKHHAEKHFPLPSSNVSVKGVLLNFEDVNGKVWRF 240
241 RYSYWNSSQSYVLTKGWSRFVKEKNLRAGDVVSFSRSNGQDQQLYIGWKSRSGSDLDAGR 300
301 VLRLFGVNISPESSRNDVVGNKRVNDTEMLSLVCSKKQRIFHAS
Interface Residues: 66, 68, 69, 70, 74, 76, 78, 81, 83, 85, 193, 195, 200, 201, 202, 204, 245, 246, 247, 248, 250
3D-footprint Homologues: 5wx9_A, 7wq5_A, 1gcc_A, 7et4_D, 6j9b_A, 7et6_A, 6sdg_B, 6fas_B, 6ycq_A, 6j9c_D
Binding Motifs: MA0582.1 / RAV1(1) mwgCAACAkwwa
MA0583.1 / RAV1(2) wtCaCCTGrssy
M0077_1.02 wwrcaaCAkw
M0078_1.02 dCACCTGAww
M0722 mwgrTdwwtTyTGTTGb
M0723 tttymagrtdwwtTyTGTTGk
MA0582.2 gCAACA
Binding Sites: MA0582.1.1
MA0582.1.10
MA0582.1.11
MA0582.1.12
MA0582.1.13
MA0582.1.14
MA0582.1.15
MA0582.1.16
MA0582.1.17
MA0582.1.18
MA0582.1.19
MA0582.1.2
MA0582.1.20
MA0582.1.3
MA0582.1.4
MA0582.1.5
MA0582.1.6
MA0582.1.7
MA0582.1.8
MA0582.1.9
MA0582.2.9
MA0582.2.19
MA0582.2.1
MA0582.2.10
MA0582.2.11
MA0582.2.12
MA0582.2.13
MA0582.2.14
MA0582.2.15
MA0582.2.16
MA0582.2.17
MA0582.2.18
MA0582.2.2 / MA0582.2.4
MA0582.2.20
MA0582.2.3
MA0582.2.5
MA0582.2.6 / MA0582.2.7
MA0582.2.8
Publications: Kagaya Y., Ohmiya K., Hattori T. RAV1, a Novel DNA-Binding Protein, Binds to Bipartite Recognition Sequence through Two Distinct DNA-Binding Domains Uniquely Found in Higher Plants. Nucleic Acids Res. 27:470-478 (1999). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.