Transcription Factor
| Accessions: | UP00417A (UniPROBE 20160601) |
| Names: | AW414408, E1AF), ETS translocation variant 4, ets variant gene 4 (E1A enhancer binding protein, Etv4, Pea-3, Pea3, Polyomavirus enhancer activator 3, Protein PEA3 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q3TYM4 |
| Description: | ets variant gene 4 (E1A enhancer binding protein, E1AF): ETS translocation variant 4 |
| Length: | 116 |
| Pfam Domains: | 17-98 Ets-domain |
| Sequence: (in bold interface residues) | 1 GIGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQ 60 61 KNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPAL |
| Interface Residues: | 69, 70, 72, 73, 74, 76, 77, 91 |
| 3D-footprint Homologues: | 1dux_F, 7jsa_J, 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C |
| Binding Motifs: | UP00417A_1 stsmAywTCCGGtggy |
| Binding Sites: | ACATCCGG ACCGGAAA ACCGGAAG ACCGGATG ACTTCCGC AGCGGAAG AGTTCCGG ATATCCGG ATCCGGAT ATTTCCGG CACCGGAA CACTTCCG CCGGAAAC CCGGAAGC CCGGATGC CTTCCGGA CTTCCGGC GACCGGAA GTTCCGGA TTCCGGAA |
| Publications: | Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed] |
| Related annotations: | PaperBLAST |
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