Transcription Factor

						

			
Accessions: ZNF238_full (HumanTF 1.0)

			
Names: 58 kDa repressor protein, TAZ-1, Transcriptional repressor RP58, Translin-associated zinc finger protein 1, Zinc finger and BTB domain-containing protein 18, Zinc finger protein 238, Zinc finger protein C2H2-171, ZN238_HUMAN, ZNF238
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q99592
Notes: Ensembl ID: ENSG00000179456; Full protein sequence; TF family: znfC2H2; Clone source: hORFeome
Length: 532
Pfam Domains:    23-129 BTB/POZ domain
  379-401 Zinc finger, C2H2 type
  380-401 C2H2-type zinc finger
  420-441 Zinc finger, C2H2 type
  421-441 C2H2-type zinc finger
  434-456 Zinc-finger double domain
  447-469 C2H2-type zinc finger
  447-469 Zinc finger, C2H2 type
  461-485 Zinc-finger double domain
  475-498 C2H2-type zinc finger
  475-498 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MCPKGYEDSMEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHL   60
  61 FYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVK  120
 121 VCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILP  180
 181 SKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVR  240
 241 DSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYD  300
 301 MEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGM  360
 361 ESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPT  420
 421 CSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWC  480
 481 ERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK*
Interface Residues: 389, 390, 391, 392, 393, 396, 397, 399, 400, 402, 403, 406, 409, 429, 430, 431, 432, 433, 435, 436, 437, 439, 442, 444, 457, 458, 459, 460, 461, 462, 463, 464, 465, 468, 485, 486, 487, 488, 489, 490, 491, 492, 496, 497, 508, 509, 510, 511, 514
3D-footprint Homologues: 7n5w_A, 7w1m_H, 2i13_A, 5yel_A, 5ei9_F, 1g2f_F, 2gli_A, 5k5l_F, 5v3j_F, 7eyi_G, 6e94_A, 7ysf_A, 6wmi_A, 1ubd_C, 2jpa_A, 1tf3_A, 3uk3_C, 6jnm_A, 8cuc_F, 7y3l_A, 4x9j_A, 8gn3_A, 1mey_C, 6blw_A, 5kkq_D, 6u9q_A, 5kl3_A, 5k5i_A, 2kmk_A, 8ssq_A, 1tf6_A, 5und_A, 8ssu_A, 6ml4_A, 8h9h_G, 4m9v_C, 7y3m_I, 2lt7_A, 6a57_A, 1yuj_A, 2wbs_A, 1f2i_J, 7txc_E, 2drp_D, 5yj3_D, 1llm_D
Binding Motifs: ZNF238_full hatCCAGATGTkb
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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