Transcription Factor

Accessions: 6o3t_A (3D-footprint 20231221)
Names: Forkhead box protein C2, Forkhead-related protein FKHL14, FOXC2_HUMAN, Mesenchyme fork head protein 1, MFH-1 protein, Transcription factor FKH-14
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q99958
Length: 95
Pfam Domains: 3-95 Fork head domain
Sequence:
(in bold interface residues)
1 LVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNEC 60
61 FVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRR
Interface Residues: 43, 46, 48, 49, 50, 52, 53, 54, 56, 57, 66, 73
3D-footprint Homologues: 3l2c_A, 7vox_H, 2hdc_A, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 3qrf_G
Binding Motifs: 6o3t_AB GTTTATAAACA
Publications: Li S, Pradhan L, Ashur S, Joshi A, Nam HJ. Crystal Structure of FOXC2 in Complex with DNA Target. ACS Omega 4:10906-10914 (2019). [Pubmed]
Related annotations: PaperBLAST

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