Transcription Factor

Accessions: ZSCAN9 (HT-SELEX2 May2017)
Names: ENSG00000137185, ZSCAN9
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: SCAN_Znf_C2H2 experiment: HT-SELEX Hamming distance: 2 cycle: 3, TF family: SCAN_Znf_C2H2 experiment: Methyl-HT-SELEX Hamming distance: 2 cycle: 3
Length: 159
Pfam Domains: 19-39 C2H2-type zinc finger
19-41 Zinc finger, C2H2 type
19-41 C2H2-type zinc finger
34-58 Zinc-finger double domain
46-66 C2H2-type zinc finger
47-69 Zinc finger, C2H2 type
47-66 C2H2-type zinc finger
64-85 Zinc-finger double domain
75-97 C2H2-type zinc finger
75-97 Zinc finger, C2H2 type
75-97 C2H2-type zinc finger
90-113 Zinc-finger double domain
103-125 C2H2-type zinc finger
103-125 Zinc finger, C2H2 type
103-125 C2H2-type zinc finger
120-141 Zinc-finger double domain
130-151 C2H2-type zinc finger
131-153 Zinc finger, C2H2 type
131-153 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 EHKDRIERQWGNLLGEGQHKCDECGKSFTQSSGLIRHQRIHTGERPYECNECGKAFSRSS 60
61 GLFNHRGIHNIQKRYHCKECGKVFSQSAGLIQHQRIHKGEKPYQCSQCSKSYSRRSFLIE 120
121 HQRSHTGERPHQCIECGKSFNRHCNLIRHQKIHTVAELV
Interface Residues: 5, 8, 29, 30, 31, 32, 33, 34, 35, 36, 38, 39, 40, 42, 47, 57, 58, 59, 60, 61, 63, 64, 68, 85, 86, 87, 88, 89, 92, 95, 96, 113, 114, 115, 116, 117, 119, 120, 121, 141, 142, 143, 144, 145, 146, 147, 148, 149
3D-footprint Homologues: 8ssq_A, 5und_A, 8ssu_A, 3uk3_C, 8cuc_F, 7y3l_A, 5v3j_F, 6u9q_A, 5ei9_F, 6wmi_A, 5k5i_A, 7w1m_H, 2gli_A, 1tf6_A, 8gn3_A, 6blw_A, 5kkq_D, 7eyi_G, 7y3m_I, 6e94_A, 7ysf_A, 2i13_A, 5yel_A, 2jpa_A, 2kmk_A, 5yj3_D, 6ml4_A, 2lt7_A, 1ubd_C, 1tf3_A, 6jnm_A, 7n5w_A, 1mey_C, 7txc_E, 5kl3_A, 1f2i_J, 1g2f_F, 5k5l_F, 4x9j_A, 8h9h_G, 6a57_A, 2wbs_A, 2drp_D, 1llm_D, 4m9v_C
Binding Motifs: ZSCAN9_2 rrgGATAAGATAAGAAtCay
ZSCAN9_methyl_1 raGGATAAGATAAGAAkCay
Related annotations: PaperBLAST

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