Transcription Factor
| Accessions: | MAZ_HUMAN (HOCOMOCO 10), P56270 (JASPAR 2024) |
| Names: | MAZ_HUMAN, MAZI, Myc-associated zinc finger protein, Pur-1, Purine-binding transcription factor, SAF-1, Serum amyloid A-activating factor-1, Transcription factor Zif87, ZF87, Zinc finger protein 801 |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 477 |
| Pfam Domains: | 190-212 C2H2-type zinc finger 190-212 Zinc finger, C2H2 type 279-301 C2H2-type zinc finger 279-301 Zinc finger, C2H2 type 293-318 Zinc-finger double domain 307-329 Zinc finger, C2H2 type 307-329 C2H2-type zinc finger 322-348 Zinc-finger double domain 337-360 C2H2-type zinc finger 337-360 Zinc finger, C2H2 type 351-377 Zinc-finger double domain 366-385 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MFPVFPCTLLAPPFPVLGLDSRGVGGLMNSFPPPQGHAQNPLQVGAELQSRFFASQGCAQ 60 61 SPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAAS 120 121 TVDTAALKQPPAPPPPPPPVSAPAAEAAPPASAATIAAAAATAVVAPTSTVAVAPVASAL 180 181 EKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVPLSLLSVPQ 240 241 LSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGKRIRKNHACEMCGKAFRDVYHLNRHKLS 300 301 HSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVHKPYNCSHCGKSFSRPDHLNSHVRQVH 360 361 STERPFKCEKCEAAFATKDRLRAHTVRHEEKVPCHVCGKMLSSAYISDHMKVHSQGPHHV 420 421 CELCNKGTGEVCPMAAAAAAAAAAAAAAVAAPPTAVGSLSGAEGVPVSSQPLPSQPW |
| Interface Residues: | 172, 174, 175, 176, 178, 182, 200, 201, 203, 204, 207, 221, 224, 227, 228, 229, 230, 232, 244, 247, 248, 249, 250, 260, 261, 262, 263, 264, 265, 267, 269, 270, 271, 273, 289, 290, 291, 292, 293, 295, 296, 297, 298, 299, 302, 317, 318, 319, 320, 321, 322, 323, 324, 325, 327, 347, 348, 349, 350, 351, 352, 353, 354, 357, 376, 377, 378, 379, 380, 382, 383, 387, 402, 403, 404, 405, 407, 408, 409 |
| 3D-footprint Homologues: | 8ssu_A, 8ssq_A, 7w1m_H, 5v3j_F, 5kkq_D, 6jnm_A, 7n5w_A, 5und_A, 2gli_A, 1g2f_F, 6ml4_A, 6blw_A, 1ubd_C, 6u9q_A, 5ei9_F, 1mey_C, 5kl3_A, 6wmi_A, 5k5i_A, 2kmk_A, 4m9v_C, 7eyi_G, 8h9h_G, 2lt7_A, 1tf6_A, 2i13_A, 6e94_A, 7ysf_A, 1tf3_A, 6a57_A, 2jpa_A, 4x9j_A, 8gn3_A, 1llm_D, 2wbs_A, 5yel_A, 7txc_E, 2drp_D, 1f2i_J, 8cuc_F, 7y3l_A, 3uk3_C, 5k5l_F, 5yj3_D, 7y3m_I |
| Binding Motifs: | MAZ_HUMAN.H10MO.A|M01315 GGGmGGGGssggggggGgGgGg MA1522.1 ssCCCCTCCcc MA1522.2 CCCCTCCc |
| Binding Sites: | MA1522.2.1 / MA1522.2.10 / MA1522.2.11 / MA1522.2.12 / MA1522.2.19 / MA1522.2.4 / MA1522.2.5 / MA1522.2.6 / MA1522.2.9 MA1522.1.1 MA1522.1.10 / MA1522.1.12 MA1522.1.11 / MA1522.1.13 MA1522.1.12 / MA1522.1.15 MA1522.1.13 / MA1522.1.17 MA1522.1.14 / MA1522.1.19 MA1522.1.15 MA1522.1.16 MA1522.1.17 MA1522.1.18 MA1522.1.19 MA1522.1.2 / MA1522.1.3 MA1522.1.20 MA1522.1.3 / MA1522.1.4 MA1522.1.4 / MA1522.1.5 MA1522.1.5 / MA1522.1.6 MA1522.1.6 / MA1522.1.7 MA1522.1.10 / MA1522.1.7 / MA1522.1.8 / MA1522.1.9 MA1522.1.11 / MA1522.1.9 MA1522.1.14 MA1522.1.16 MA1522.1.18 MA1522.1.2 MA1522.1.20 MA1522.1.8 MA1522.2.13 / MA1522.2.15 / MA1522.2.17 MA1522.2.14 / MA1522.2.16 MA1522.2.18 MA1522.2.2 MA1522.2.20 MA1522.2.3 MA1522.2.7 MA1522.2.8 |
| Publications: | Duncan D. D., Stupakoff A., Hedrick S. M., Marcu K. B., Siu G. A myc-associated zinc finger protein binding site is one of four important functional regions inthe CD4 promoter. Mol. Cell. Biol. 15:3179-3186 (1995). [Pubmed] |
| Related annotations: | PaperBLAST |
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