Transcription Factor
| Accessions: | ZIC3_full (HumanTF 1.0) |
| Names: | ZIC3, ZIC3_HUMAN, Zinc finger protein 203, Zinc finger protein of the cerebellum 3, Zinc finger protein ZIC 3 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Uniprot: | O60481 |
| Notes: | Ensembl ID: ENSG00000156925; Full protein sequence; TF family: znfC2H2; Clone source: hORFeome |
| Length: | 468 |
| Pfam Domains: | 297-322 Zinc finger, C2H2 type 301-322 C2H2-type zinc finger 315-340 Zinc-finger double domain 328-352 C2H2-type zinc finger 328-352 Zinc finger, C2H2 type 344-371 Zinc-finger double domain 358-382 C2H2-type zinc finger 376-399 Zinc-finger double domain 388-410 C2H2-type zinc finger 388-410 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPFGDSTHAAAAAAAAAAFKLSP 60 61 AAAHDLSSGQSSAFTPQGSGYANALGHHHHHHHHHHHTSQVPSYGGAASAAFNSTREFLF 120 121 RQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVD 180 181 NNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHGPGAFF 240 241 RYMRQPIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWE 300 301 ECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKC 360 361 EFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHESQGSDSSPA 420 421 ASSGYESSTPPAIASANSKDTTKTPSAVQTSTSHNPGLPPNFNEWYV* |
| Interface Residues: | 242, 243, 244, 274, 276, 277, 280, 310, 311, 312, 313, 314, 316, 317, 321, 328, 340, 341, 342, 343, 344, 346, 347, 348, 349, 350, 352, 353, 356, 365, 370, 371, 372, 373, 374, 375, 376, 377, 378, 381, 398, 399, 400, 401, 402, 403, 404, 405, 406 |
| 3D-footprint Homologues: | 5v3j_F, 6wmi_A, 5yel_A, 1ubd_C, 7w1m_H, 8cuc_F, 1tf3_A, 7n5w_A, 8ssq_A, 6ml4_A, 4x9j_A, 5kkq_D, 8ssu_A, 5ei9_F, 2gli_A, 1tf6_A, 7eyi_G, 8h9h_G, 2i13_A, 7ysf_A, 8gn3_A, 6e94_A, 5k5i_A, 2lt7_A, 2kmk_A, 7y3l_A, 3uk3_C, 6jnm_A, 5und_A, 1llm_D, 2v6e_B, 1mey_C, 6blw_A, 5kl3_A, 1g2f_F, 6u9q_A, 7y3m_I, 6a57_A, 2jpa_A, 6sjf_B, 5k5l_F, 2wbs_A, 2drp_D, 1f2i_J, 5yj3_D, 7txc_E, 4m9v_C |
| Binding Motifs: | ZIC3_full gACCCCCYGCtGyGh |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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