Transcription Factor

Accessions: 4u0y_A (3D-footprint 20231221), 4u0y_B (3D-footprint 20231221), 4u0y_C (3D-footprint 20231221)
Names: HTH-type transcriptional repressor NagR, HTH-type transcriptional repressor YvoA, N-acetylglucosamine utilization regulator, NAGR_BACSU
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: O34817
Length: 75
Pfam Domains: 12-74 Bacterial regulatory proteins, gntR family
39-73 DeoR-like helix-turn-helix domain
Sequence:
(in bold interface residues)
1 MNINKQSPIPIYYQIMEQLKTQIKNGELQPDMPLPSEREYAEQFGISRMTVRQALSNLVN 60
61 EGLLYRLKGRGTFVS
Interface Residues: 12, 36, 37, 38, 41, 47, 48, 49, 50, 51, 52, 53, 56, 68, 69
3D-footprint Homologues: 7zla_B, 6wg7_G, 4h0e_A, 4wwc_B, 4p9u_F, 1h9t_B, 6za3_B, 4u0y_B, 4i2o_B, 3wgi_D
Binding Motifs: 4u0y_ABCD GTGGycTAgaCCAC
4u0y_B TGGyaTA
Binding Sites: 4u0y_E / 4u0y_F
Publications: Fillenberg S.B, Grau F.C, Seidel G, Muller Y.A. Structural insight into operator dre-sites recognition and effector binding in the GntR/HutC transcription regulator NagR. Nucleic acids research 43:1283-96 (2015). [Pubmed]
Related annotations: PaperBLAST

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