Transcription Factor
| Accessions: | LHX3_HUMAN (HOCOMOCO 10) |
| Names: | LHX3_HUMAN, LIM homeobox protein 3, LIM/homeobox protein Lhx3 |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] |
| Length: | 397 |
| Pfam Domains: | 31-86 LIM domain 90-147 LIM domain 158-214 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MLLETGLERDRARPGAAAVCTLGGTREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSD 60 61 CHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVV 120 121 CKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSP 180 181 KPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKS 240 241 DKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGL 300 301 AGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRV 360 361 LAGNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF |
| Interface Residues: | 158, 159, 160, 161, 199, 200, 202, 203, 206, 207, 210, 211, 214 |
| 3D-footprint Homologues: | 1puf_A, 5zjt_E, 2h1k_B, 1fjl_B, 6a8r_A, 3cmy_A, 1ig7_A, 3d1n_M, 5zfz_A, 1jgg_B, 6m3d_C, 3lnq_A, 2lkx_A, 1zq3_P, 2ld5_A, 7q3o_C, 6es3_K, 2d5v_B, 5flv_I, 3l1p_A, 3a01_E, 6ryd_F, 1au7_A, 5hod_A, 1puf_B, 2hdd_A, 6wig_A, 1b72_A, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 7psx_B, 4cyc_A, 1e3o_C, 1le8_A, 7xrc_C, 2xsd_C, 4qtr_D, 4xrm_B, 1nk2_P, 8g87_X, 1o4x_A, 1du0_A |
| Binding Motifs: | LHX3_HUMAN.H10MO.C|M01299 aaAaTTAATTAry |
| Related annotations: | PaperBLAST |
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