Transcription Factor

						

			
Accessions: VAX2_DBD (HumanTF 1.0)

			
Names: VAX2, VAX2_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q9UIW0
Notes: Ensembl ID: ENSG00000116035; DNA-binding domain sequence; TF family: homeodomain; Clone source: MGC
Length: 112
Pfam Domains:     28-84 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MARILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTEL   60
  61 ARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATSNILRLLE
Interface Residues: 28, 29, 30, 31, 69, 70, 72, 73, 76, 77, 80, 81, 84
3D-footprint Homologues: 1puf_A, 3cmy_A, 5zfz_A, 3d1n_M, 1nk2_P, 1fjl_B, 1ig7_A, 6a8r_A, 2h1k_B, 3lnq_A, 2lkx_A, 1jgg_B, 6m3d_C, 1zq3_P, 6es3_K, 7q3o_C, 5jlw_D, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 1au7_A, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 7psx_B, 1b72_A, 5hod_A, 3l1p_A, 2ld5_A, 3a01_E, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 1le8_B, 1du0_A, 1mnm_C, 1puf_B, 1k61_B, 8g87_X, 1o4x_A, 4qtr_D
Binding Motifs: VAX2_DBD yTAATkAc
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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