Transcription Factor

Accessions: P70354 (JASPAR 2024)
Names: MSX3_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 204
Pfam Domains: 88-144 Homeobox domain
Sequence:
(in bold interface residues)
1 MARATFDMNAAGLEARGGGHTEHGPLPFSVESLLEAERVPGSESGELGVERPLGASKPGA 60
61 WPPPVAHSCPPRAPSPPPCTLRKHKTNRKPRTPFTTAQLLALERKFHQKQYLSIAERAEF 120
121 SSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKLAAKPLLPAAFALPFPLGTQLHSSAA 180
181 TFGGNAVPGILAGPVAAYGMYYLS
Interface Residues: 88, 89, 90, 91, 129, 130, 132, 133, 136, 137, 140, 141, 144
3D-footprint Homologues: 1ig7_A, 6a8r_A, 3cmy_A, 1puf_A, 3d1n_M, 5zfz_A, 1fjl_B, 2h1k_B, 2lkx_A, 1zq3_P, 6m3d_C, 1nk2_P, 3lnq_A, 7q3o_C, 6es3_K, 2ld5_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1jgg_B, 4xrs_G, 2hos_A, 4cyc_A, 1au7_A, 5flv_I, 5zjt_E, 4j19_B, 3a01_E, 7psx_B, 1b72_A, 5hod_A, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 1o4x_A, 4qtr_D, 1le8_B, 1du0_A, 1mnm_C, 1k61_B, 3l1p_A, 8g87_X
Binding Motifs: MA0709.1 syAATTAr
PH0108.1 mamAAcyAATTAAktw
MA0709.2 yAATTA
Publications: Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed]

Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.