Transcription Factor
| Accessions: | T098489_1.02 (CISBP 1.02), Q9VJ02 (JASPAR 2024) |
| Names: | Lim3, T098489_1.02;, Q9VJ02_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9VJ02 |
| Notes: | experiment type:PBM, family:Homeodomain |
| Length: | 440 |
| Pfam Domains: | 42-96 LIM domain 101-158 LIM domain 177-233 Homeobox domain 199-229 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 MELLKLMMFKSDFLSNGKCDDRVPPINLSQLPEFLLSTIPKCGGCHELILDRFILKVLER 60 61 TWHAKCLQCSECHGQLNDKCFARNGQLFCKEDFFKRYGTKCSACDMGIPPTQVVRRAQDN 120 121 VYHLQCFLCAMCSRTLNTGDEFYLMEDRKLICKRDYEEAKAKGLYLDGSLDGDQPNKRPR 180 181 TTITAKQLETLKTAYNNSPKPARHVREQLSQDTGLDMRVVQVWFQNRRAKEKRLKKDAGR 240 241 TRWSQYFRSMKGNCSPRTDKFLDKDELKVDYDSFSHHDLSNDSYSTVNLGLDEGASPHSI 300 301 RGSYMHGSSSPSQYPPSSRSPPPVGQGHTFGSYPDNIVYTNIDQAVGSSLHASKAHHRLH 360 361 SSNNVSDLSNDSSPDQGYPDFPPSPDSWLGDSGSTNTTSANNNANNNSSSSHNNNNSSGG 420 421 GSGGVSVSTAPNPSAPGVHY |
| Interface Residues: | 176, 177, 178, 179, 180, 218, 219, 221, 222, 225, 226, 229, 230, 233 |
| 3D-footprint Homologues: | 3a01_E, 5zfz_A, 1puf_A, 1fjl_B, 5zjt_E, 2h1k_B, 1ig7_A, 6a8r_A, 3cmy_A, 6m3d_C, 3lnq_A, 2lkx_A, 1zq3_P, 1jgg_B, 2ld5_A, 3d1n_M, 4cyc_A, 2d5v_B, 1au7_A, 5flv_I, 3l1p_A, 7q3o_C, 6ryd_F, 1b72_A, 5hod_A, 1puf_B, 2hdd_A, 1nk2_P, 6wig_A, 5jlw_D, 3rkq_B, 2r5y_A, 6es3_K, 4xrs_G, 2hos_A, 7psx_B, 1e3o_C, 2xsd_C, 1le8_A, 7xrc_C, 1k61_B, 4qtr_D, 4xrm_B, 1du0_A, 8g87_X, 1o4x_A |
| Binding Motifs: | MA0195.1 yTAATTA M1092_1.02 cyaaTywvsy MA0195.2 TAATTA |
| Binding Sites: | MA0195.2.4 MA0195.1.18 MA0195.1.1 MA0195.1.10 MA0195.1.11 MA0195.1.12 MA0195.1.13 MA0195.1.14 MA0195.1.15 MA0195.1.16 MA0195.1.17 MA0195.1.19 MA0195.1.2 MA0195.1.20 MA0195.1.3 MA0195.1.4 MA0195.1.5 MA0195.1.6 MA0195.1.7 MA0195.1.8 MA0195.1.9 MA0195.2.15 / MA0195.2.18 MA0195.2.20 MA0195.2.17 MA0195.2.10 MA0195.2.1 MA0195.2.11 MA0195.2.12 MA0195.2.13 MA0195.2.14 / MA0195.2.16 MA0195.2.19 MA0195.2.2 MA0195.2.3 MA0195.2.5 MA0195.2.6 MA0195.2.7 MA0195.2.8 MA0195.2.9 |
| Publications: | Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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