Transcription Factor
| Accessions: | Q9UJL9 (JASPAR 2024) |
| Names: | ZF69B_HUMAN, Zinc finger protein 643, Zinc finger protein 69 homolog B |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9UJL9 |
| Length: | 534 |
| Pfam Domains: | 2-41 SCAN domain 74-114 KRAB box 265-290 Zinc-finger double domain 278-299 C2H2-type zinc finger 279-301 Zinc finger, C2H2 type 279-301 C2H2-type zinc finger 293-317 Zinc-finger double domain 307-329 Zinc finger, C2H2 type 307-329 C2H2-type zinc finger 307-327 C2H2-type zinc finger 325-346 Zinc-finger double domain 334-353 C2H2-type zinc finger 335-357 Zinc finger, C2H2 type 335-357 C2H2-type zinc finger 349-373 Zinc-finger double domain 362-385 C2H2-type zinc finger 363-385 C2H2-type zinc finger 363-385 Zinc finger, C2H2 type 378-400 Zinc-finger double domain 390-400 C2H2-type zinc finger 391-413 C2H2-type zinc finger 391-413 Zinc finger, C2H2 type 405-430 Zinc-finger double domain 419-441 C2H2-type zinc finger 419-441 C2H2-type zinc finger 419-441 Zinc finger, C2H2 type 434-457 Zinc-finger double domain 446-457 C2H2-type zinc finger 447-469 Zinc finger, C2H2 type 447-469 C2H2-type zinc finger 461-486 Zinc-finger double domain 474-493 C2H2-type zinc finger 475-497 Zinc finger, C2H2 type 475-497 C2H2-type zinc finger 490-514 Zinc-finger double domain 503-525 C2H2-type zinc finger 503-525 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MLQQLLITLPTEASTWVKLRHPKAATERVALWEDVTKMFKAEALLSQDADETQGESLESR 60 61 VTLGSLTAESQELLTFKDVSVDFTQEEWGQLAPAHRNLYREVMLENYGNLVSVGCQLSKP 120 121 GVISQLEKGEEPWLMERDISGVPSSDLKSKTKTKESALQNDISWEELHCGLMMERFTKGS 180 181 SMYSTLGRISKCNKLESQQENQRMGKGQIPLMCKKTFTQERGQESNRFEKRINVKSEVMP 240 241 GPIGLPRKRDRKYDTPGKRSRYNIDLVNHSRSYTKMKTFECNICEKIFKQLIHLTEHMRI 300 301 HTGEKPFRCKECGKAFSQSSSLIPHQRIHTGEKPYECKECGKTFRHPSSLTQHVRIHTGE 360 361 KPYECRVCEKAFSQSIGLIQHLRTHVREKPFTCKDCGKAFFQIRHLRQHEIIHTGVKPYI 420 421 CNVCSKTFSHSTYLTQHQRTHTGERPYKCKECGKAFSQRIHLSIHQRVHTGVKPYECSHC 480 481 GKAFRHDSSFAKHQRIHTGEKPYDCNECGKAFSCSSSLIRHCKTHLRNTFSNVV |
| Interface Residues: | 44, 47, 48, 76, 95, 97, 261, 265, 289, 290, 291, 292, 293, 295, 296, 298, 299, 300, 302, 307, 317, 318, 319, 320, 321, 323, 324, 325, 345, 346, 347, 348, 349, 350, 352, 353, 373, 374, 375, 376, 377, 379, 380, 401, 402, 403, 404, 405, 407, 408, 429, 430, 432, 433, 436, 439, 442, 456, 458, 459, 460, 461, 464, 468, 485, 486, 487, 488, 489, 490, 491, 492, 513, 514, 515, 516, 517, 519, 520 |
| 3D-footprint Homologues: | 4ofa_A, 7w1m_H, 7n5w_A, 8ssu_A, 5k5i_A, 8ssq_A, 1llm_D, 8h9h_G, 7eyi_G, 6wmi_A, 2jpa_A, 1ubd_C, 2kmk_A, 1tf3_A, 6ml4_A, 5v3j_F, 1mey_C, 2drp_D, 6u9q_A, 5kl3_A, 5und_A, 2i13_A, 4m9v_C, 7y3l_A, 3uk3_C, 2wbs_A, 4x9j_A, 1f2i_J, 5k5l_F, 5kkq_D, 1tf6_A, 5yel_A, 6blw_A, 2lt7_A, 6jnm_A, 5ei9_F, 2gli_A, 7y3m_I, 6e94_A, 7ysf_A, 6a57_A, 7txc_E, 1g2f_F, 5yj3_D, 8cuc_F, 8gn3_A |
| Binding Motifs: | UN0156.1 gwkrCTGGAAACAAGmt UN0589.1 GTGGCTGGA UN0156.2 gwkrCTGGAAACAAG |
| Binding Sites: | UN0156.1.1 UN0156.1.10 / UN0156.1.11 UN0156.1.11 / UN0156.1.12 UN0156.1.12 / UN0156.1.13 UN0156.1.13 / UN0156.1.14 UN0156.1.14 / UN0156.1.15 UN0156.1.15 / UN0156.1.16 UN0156.1.16 / UN0156.1.17 UN0156.1.17 / UN0156.1.18 UN0156.1.18 / UN0156.1.19 UN0156.1.19 / UN0156.1.20 UN0156.1.2 UN0156.1.20 UN0156.1.3 / UN0156.1.4 UN0156.1.4 / UN0156.1.5 UN0156.1.5 / UN0156.1.6 UN0156.1.6 / UN0156.1.7 UN0156.1.7 / UN0156.1.9 UN0156.1.10 / UN0156.1.8 UN0156.1.9 UN0156.1.2 UN0156.1.3 UN0156.1.8 UN0156.2.1 / UN0156.2.19 / UN0156.2.2 UN0156.2.10 / UN0156.2.12 UN0156.2.11 UN0156.2.13 UN0156.2.14 UN0156.2.15 UN0156.2.16 UN0156.2.17 UN0156.2.18 UN0156.2.20 UN0156.2.3 UN0156.2.4 UN0156.2.5 UN0156.2.6 UN0156.2.7 UN0156.2.8 UN0156.2.9 |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.