Transcription Factor

						

			
Accessions: 4uuv_J (3D-footprint 20231221), 4uuv_M (3D-footprint 20231221), 4uuv_V (3D-footprint 20231221)

			
Names: Adenovirus E1A enhancer-binding protein, E1A-F, ETS TRANSLOCATION VARIANT 4, ETV4_HUMAN, Polyomavirus enhancer activator 3 homolog, Protein PEA3
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P43268
Length: 94
Pfam Domains:      2-82 Ets-domain
Sequence: 
(in bold interface residues)		   1 LQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLR   60
  61 YYYEKGIMQKVAGERYVYKFVCEPDALFSMAFPD
Interface Residues: 53, 54, 56, 57, 58, 60, 61, 75
3D-footprint Homologues: 1dux_F, 7jsa_J, 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C
Binding Motifs: 4uuv_AM ACnTCCGnnnnCGGAaGt
4uuv_GJ TCCGnTAnCGGAnGA
4uuv_SV CGGAAnTnnnCGGAnG
Binding Sites: 4uuv_T
4uuv_W
4uuv_X
4uuv_U
4uuv_K
4uuv_L
4uuv_N
4uuv_O
			
Publications: Cooper C.D, Newman J.A, Aitkenhead H, Allerston C.K, Gileadi O. Structures of the Ets Domains of Transcription Factors ETV1, ETV4, ETV5 and FEV: Determinants of DNA Binding and Redox Regulation by Disulfide bond formation. The Journal of biological chemistry : (2015). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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