Transcription Factor
| Accessions: | UP00505A (UniPROBE 20160601) |
| Names: | 10.5, 10.9, 14.10, 20.35, CG2328, Dmel\CG2328, E(eve), Eve, eve2, Even skipped, l(2)46Ce, l(2)46CFg, l(2)46CFh, l(2)46CFj, l(2)46CFp, l(2)46Cg, Segmentation protein even-skipped, VI |
| Organisms: | Drosophila melanogaster |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Description: | Even skipped: Even skipped may play a role in determining neuronal identity. It may be directly involved in specifying identity of individual neurons and is required for segmentation; involved in transforming the broad, spatial, aperiodic expression patterns of the gap genes into a system of precise periodic expression patterns of the pair-rule and segmentary polarity genes. |
| Length: | 89 |
| Pfam Domains: | 16-72 Homeobox domain |
| Sequence: (in bold interface residues) | 1 LNGSRGSEIPADPSVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIK 60 61 VWFQNRRMKDKRQRIAVAWPYAAVYSDPA |
| Interface Residues: | 16, 17, 18, 19, 26, 29, 30, 32, 33, 57, 58, 60, 61, 64, 65, 68, 69, 72 |
| 3D-footprint Homologues: | 1fjl_B, 1puf_A, 1ig7_A, 6a8r_A, 2h1k_B, 3cmy_A, 5zfz_A, 1zq3_P, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 3d1n_M, 2ld5_A, 7q3o_C, 6es3_K, 5zjt_E, 4cyc_A, 7psx_B, 1b72_A, 5hod_A, 3l1p_A, 3a01_E, 1mnm_C, 5jlw_D, 1puf_B, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 6m3d_C, 5flv_I, 2hos_A, 1yo5_C, 2xsd_C, 1le8_A, 7xrc_C, 1e3o_C, 1au7_A, 1o4x_A, 8g87_X, 4qtr_D, 1du0_A, 1k61_B |
| Binding Motifs: | UP00505A_1 mmtwvasCTAATTAGygrdrct |
| Binding Sites: | GGTAATTA AATAATTA ACTAATTA AGTAATTA ATAATTAA ATAATTAC ATAATTAG ATTAATTA CCTAATTA CTAATTAA CTAATTAC CTAATTAG CTTAATTA GATAATTA GCTAATTA GTAATTAA GTAATTAC GTTAATTA TAATTAGA TTAATTAA |
| Publications: | Busser BW, Shokri L, Jaeger SA, Gisselbrecht SS, Singhania A, Berger MF, Zhou B, Bulyk ML, Michelson AM. Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development 139:1164-74 (2012). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.