Transcription Factor

Accessions: ZNF385D (HT-SELEX2 May2017)
Names: ENSG00000151789, ZNF385D
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: Znf_U1 experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: Znf_U1 experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3
Length: 247
Pfam Domains: 21-44 Zinc-finger of C2H2 type
138-174 C2H2 type zinc-finger (2 copies)
144-168 Zinc-finger of C2H2 type
205-236 C2H2 type zinc-finger (2 copies)
207-231 Zinc-finger of C2H2 type
207-232 Zinc-finger double-stranded RNA-binding
Sequence:
(in bold interface residues)
1 KAVINHTFGVPLPHRRKQIISCNICQLRFNSDSQAAAHYKGTKHAKKLKALEAMKNKQKS 60
61 VTAKDSAKTTFTSITTNTINTSSDKTDGTAGTPAISTTTTVEIRKSSVMTTEITSKVEKS 120
121 PTTATGNSSCPSTETEEEKAKRLLYCSLCKVAVNSASQLEAHNSGTKHKTMLEARNGSGT 180
181 IKAFPRAGVKGKGPVNKGNTGLQNKTFHCEICDVHVNSETQLKQHISSRRHKDRAAGKPP 240
241 KPKYSPY
Interface Residues: 31, 32, 33, 34, 52, 53, 56, 57, 216, 220
3D-footprint Homologues: 7eyi_G, 7n5w_A, 8h9h_G, 6rwn_I, 7w1m_H
Binding Motifs: ZNF385D_2 myGTCGCGACrk
ZNF385D_methyl_1 yCGTCGCGACGr
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.