Transcription Factor

Accessions: DMRTA2 (HT-SELEX2 May2017)
Names: DMRTA2, ENSG00000142700
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: DM experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: DM experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4
Length: 81
Pfam Domains: 21-67 DM DNA binding domain
Sequence:
(in bold interface residues)
1 VAGGLLRGPPLLLRAAEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAER 60
61 QRVMAAQVALRRQQAQEENEA
Interface Residues: 21, 60, 64, 67, 68, 71, 72
3D-footprint Homologues: 4yj0_C
Binding Motifs: DMRTA2_2 aattGwTACAwt
DMRTA2_methyl_1 aattGwTACAwt
Related annotations: PaperBLAST

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