Transcription Factor
| Accessions: | TFEB (HT-SELEX2 May2017) |
| Names: | ENSG00000112561, TFEB |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: bHLH experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: bHLH experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3 |
| Length: | 133 |
| Pfam Domains: | 30-83 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 VTSSSCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKAN 60 61 DLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVH 120 121 GLPTTSPSGMNMA |
| Interface Residues: | 31, 34, 35, 37, 38, 41, 42, 66, 68, 90, 91, 118 |
| 3D-footprint Homologues: | 1a0a_B, 7rcu_E, 8osl_O, 6g1l_A, 5eyo_A, 7ssa_L, 5nj8_D, 4h10_A, 7d8t_A, 5gnj_I, 1am9_A, 5v0l_A, 4h10_B, 7f2f_B, 5i50_B, 7xi3_A, 4zpk_A, 8osl_P, 1an4_A, 2ypa_A, 5nj8_C, 5v0l_B, 7ubl_A |
| Binding Motifs: | TFEB_2 yvCACGTGAys TFEB_methyl_1 amCATGTGAcy |
| Related annotations: | PaperBLAST |
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