Transcription Factor
| Accessions: | 1cdw_A (3D-footprint 20231221) |
| Names: | TATA BINDING PROTEIN (TBP), TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP_HUMAN, Transcription initiation factor TFIID TBP subunit |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P20226 |
| Length: | 179 |
| Pfam Domains: | 5-87 Transcription factor TFIID (or TATA-binding protein, TBP) 93-177 Transcription factor TFIID (or TATA-binding protein, TBP) |
| Sequence: (in bold interface residues) | 1 SGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGK 60 61 MVCTGAKSEENSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQ 120 121 QFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRK |
| Interface Residues: | 9, 11, 39, 40, 54, 56, 62, 64, 98, 99, 101, 130, 131, 145, 147, 153, 155 |
| 3D-footprint Homologues: | 6cnb_R, 1cdw_A, 5iy6_P, 7z7n_D, 1qna_B, 5n9g_G, 1ytb_A, 5oqj_O, 1ais_A, 4wzs_D |
| Binding Motifs: | 1cdw_A TATAAaAg |
| Binding Sites: | 1cdw_B 1cdw_C |
| Publications: | Nikolov D.B, Chen H, Halay E.D, Hoffman A, Roeder R.G, Burley S.K. Crystal structure of a human TATA box-binding protein/TATA element complex. Proceedings of the National Academy of Sciences of the United States of America 93:4862-7 (1996). [Pubmed] |
| Related annotations: | PaperBLAST |
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