Transcription Factor
| Accessions: | UP00074A (UniPROBE 20160601) |
| Names: | IFN-alpha-responsive transcription factor subunit, interferon dependent positive acting transcription factor 3 gamma, Interferon-stimulated gene factor 3 gamma, Irf-9, ISGF-3 gamma, ISGF3 p48 subunit, Isgf3g, Transcriptional regulator ISGF3 gamma subunit |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q61179 |
| Description: | interferon dependent positive acting transcription factor 3 gamma: Mus musculus interferon dependent positive acting transcription factor 3 gamma (Isgf3g), mRNA |
| Length: | 131 |
| Pfam Domains: | 10-115 Interferon regulatory factor transcription factor |
| Sequence: (in bold interface residues) | 1 ASGKVRCTRKLRSWIVEQVESGHFPGVCWDDAAKTMFRIPWKHAGKQDFREDQDAAIFKA 60 61 WALFKEKHKDGDIGHPAVWKTRLRCALNKSSEFEEVPERGRMDVAEPYKVYRILPAGTLP 120 121 NQPRNQKSPCK |
| Interface Residues: | 43, 45, 77, 81, 82, 84, 85, 88, 89 |
| 3D-footprint Homologues: | 2pi0_B, 1if1_B, 2irf_L, 7oot_B, 2o61_A |
| Binding Motifs: | UP00074A_1 mrrAAwCGAAACyaA UP00074A_2 gsaaAAcabkactr |
| Binding Sites: | AAACGAAA AACCGAAA AACGAAAC AAGTTTCG ACCGAAAC ACGAAACT AGCGAAAC AGTTTCGA AGTTTCGC AGTTTCGG ATCGAAAC CAGTTTCG CGAAACCA CGAAACCG CGAAACTA CGAAACTC CTCGAAAC GAAACTTA GGTTTCGA GTTTCGAA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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