Transcription Factor

Accessions: 3ikt_B (3D-footprint 20231221)
Names: Redox-sensing transcriptional repressor rex, REX_THET2
Organisms: strain HB27 / ATCC BAA-163 / DSM 7039, Thermus thermophilus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q72I39
Length: 206
Pfam Domains: 2-50 Putative DNA-binding protein N-terminus
79-174 CoA binding domain
Sequence:
(in bold interface residues)
1 MKVPEAAISRLITYLRILEELEAQGVHRTSSEQLGELAQVTAFQVRKDLSYFGSYGTRGV 60
61 GYTVPVLKRELRHILGLNRKWGLCIVGMGRLGSALADYPGFGESFELRGFFDVDPEKVGR 120
121 PVRGGVIEHVDLLPQRVPGRIEIALLTVPREAAQKAADLLVAAGIKGILNFAPVVLEVPK 180
181 EVAVENVDFLAGLTRLSFAILNPKWR
Interface Residues: 43, 44, 46, 47, 50, 51, 58, 60
3D-footprint Homologues: 3wgi_D, 7wb3_B, 3ikt_B, 3ket_A
Binding Motifs: 3ikt_AB TGTGAnnnnnnTCACAGC
3ikt_B TCACAGC
Binding Sites: 3ikt_C / 3ikt_D
Publications: McLaughlin K.J, Strain-Damerell C.M, Xie K, Brekasis D, Soares A.S, Paget M.S, Kielkopf C.L. Structural basis for NADH/NAD+ redox sensing by a Rex family repressor. Molecular cell 38:563-75 (2010). [Pubmed]
Related annotations: PaperBLAST

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