Transcription Factor

						

			
Accessions: 5t01_A (3D-footprint 20231221), 5t01_B (3D-footprint 20231221)

			
Names: Activator protein 1, AP1, JUN_HUMAN, p39, Proto-oncogene c-Jun, Transcription factor AP-1, V-jun avian sarcoma virus 17 oncogene homolog
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P05412
Length: 62
Pfam Domains:      2-62 bZIP transcription factor
     4-59 Basic region leucine zipper
Sequence: 
(in bold interface residues)		   1 HMKAERKRMRNRIAASKSRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQK   60
  61 VM
Interface Residues: 7, 8, 10, 11, 12, 14, 15, 18, 19
3D-footprint Homologues: 1gd2_G, 7x5e_F, 1nwq_C, 5t01_B, 5vpe_D, 2dgc_A, 1dh3_C
Binding Motifs: 5t01_AB angAGTCAt
5t01_B TgACt
Binding Sites: 5t01_C
5t01_D
			
Publications: Hong S, Wang D, Horton JR, Zhang X, Speck SH, Blumenthal RM, Cheng X. Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta. Nucleic Acids Res 45:2503-2515 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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