Transcription Factor
Accessions: | 5t01_A (3D-footprint 20231221), 5t01_B (3D-footprint 20231221) |
Names: | Activator protein 1, AP1, JUN_HUMAN, p39, Proto-oncogene c-Jun, Transcription factor AP-1, V-jun avian sarcoma virus 17 oncogene homolog |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P05412 |
Length: | 62 |
Pfam Domains: | 2-62 bZIP transcription factor 4-59 Basic region leucine zipper |
Sequence: (in bold interface residues) | 1 HMKAERKRMRNRIAASKSRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQK 60 61 VM |
Interface Residues: | 7, 8, 10, 11, 12, 14, 15, 18, 19 |
3D-footprint Homologues: | 7x5e_F, 1gd2_G, 1nwq_C, 2dgc_A, 1dh3_C, 5t01_B, 5vpe_D |
Binding Motifs: | 5t01_AB angAGTCAt 5t01_B TgACt |
Binding Sites: | 5t01_C 5t01_D |
Publications: | Hong S, Wang D, Horton JR, Zhang X, Speck SH, Blumenthal RM, Cheng X. Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta. Nucleic Acids Res 45:2503-2515 (2017). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.